ArticleNature chemical biology2020
Activation of the α
Article in Nature chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Effect of perioperative dexmedetomidine on recovery of postoperative gastrointestinal function in patients with general anesthesia: a systematic review and meta-analysis.BMC anesthesiology · 2024Pooled it
- Opioid requirement and pain intensity after mandibular surgeries with dexmedetomidine administration in two ways: intraoperative infusion versus bolus injection.Oral and maxillofacial surgery · 2024Trial
- Impact of intravenous dexmedetomidine on gastrointestinal function recovery after laparoscopic hysteromyomectomy: a randomized clinical trial.Scientific reports · 2022Trial
- Dexmedetomidine attenuates hypoxia/reoxygenation-induced cardiomyocyte injury in association with ADRA2A/ADRA2B and Notch1/Hes1 modulation.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Article
- Association between dexmedetomidine administration and 28-day mortality in critically ill patients with ventilator-associated pneumonia.Frontiers in pharmacology · 2026Article
- Dexmedetomidine Use and Intraoperative Bradycardia During Radiofrequency Rhizotomy for Trigeminal Neuralgia: A Retrospective Observational Study.Drug design, development and therapy · 2026Observational
- Neuronal activity in the cortex of mice under anesthesia depend on the type of anesthetic drug.BMC anesthesiology · 2025Article
- Recent Developments in the Optical Control of Adrenergic Signaling.Medicinal research reviews · 2025Review
- Delirium as a mediating factor in the survival benefits of dexmedetomidine in acute brain injury management.Scientific reports · 2025Article
- Discovery and development of an oral analgesic targeting the α2B adrenoceptor.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Effect of dexmedetomidine combined with magnesium sulphate on intracranial tension in patients with severe pre-eclampsia using ultrasonographic optic nerve sheath Diameter - A randomised clinical trial.Indian journal of anaesthesia · 2025Article
- Network pharmacology and experimental validation reveal dexmedetomidine's protective mechanisms against acute liver injury in mice.Scientific reports · 2025Article
- Identification ofMolecules (Basel, Switzerland) · 2025Article
- REcovery from DEXmedetomidine-Induced Unresponsiveness (REDEX): A Study Protocol for a Single Center, Parallel Arm, Non-Randomized, Controlled Pilot Trial in Healthy Volunteers.Nature and science of sleep · 2025Article
- Anesthetic management of diabetic foot amputation in a patient with renal failure and maintenance hemodialysis: case report and short communication.American journal of translational research · 2025Article
- Classics in Chemical Neuroscience: Medetomidine.ACS chemical neuroscience · 2024Review
- Distinct binding conformations of epinephrine with α- and β-adrenergic receptors.Experimental & molecular medicine · 2024Article
- GPCR-G protein selectivity revealed by structural pharmacology.The FEBS journal · 2024Review
- The Discovery of Novel αInternational journal of molecular sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The α
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.