Evidence map›Paper›PMID 32152523›Full record

ReviewNature reviews. Neuroscience2020

Programmed axon degeneration: from mouse to mechanism to medicine.

Michael P Coleman, Ahmet Höke

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed, 1 pooled it
24.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed, 1 synthesis or guideline pooled it, 318 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Peripheral Neuropathy in Metabolic Stress.International journal of molecular sciences · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Junctions in Jeopardy: the neuromuscular junction is a selective pathological target in Charcot-Marie-Tooth disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  19. Article
  20. Article

150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Michael P ColemanJohn van Geest Centre for Brain Repair, University of Cambridge, Cambridge, United Kingdom. mc469@cam.ac.uk.ORCID http://orcid.org/0000-0002-9354-532X
Ahmet HökeNeuromuscular Division, Johns Hopkins School of Medicine, Baltimore, MD, USA. ahoke@jhmi.edu.ORCID http://orcid.org/0000-0003-1215-3373
Babraham Institute · GBJohns Hopkins University · US

Funding

Mechanism of neuroprotection in chemotherapy induced peripheral neuropathyR01NS091260 · NINDS · JOHNS HOPKINS UNIVERSITY · PI HOKE, AHMET · 2015 to 2019
$1.8M
Medical Research Council G1000702Medical Research Council MR/N004582/1NINDS NIH HHS R01 NS091260
6 · The paper itself

Abstract

Wallerian degeneration is a widespread mechanism of programmed axon degeneration. In the three decades since the discovery of the Wallerian degeneration slow (Wld

Indexed as

AnimalsArmadillo Domain ProteinsCytoskeletal ProteinsDisease Models, AnimalDrosophila melanogasterHumansMiceMice, TransgenicNADNicotinamide-Nucleotide AdenylyltransferaseSignal TransductionTranslational Research, BiomedicalWallerian DegenerationArmadillo Domain ProteinsCytoskeletal ProteinsNADNicotinamide-Nucleotide AdenylyltransferaseNMNAT2 protein, humanSARM1 protein, human

Identifiers

PMID32152523
PMCPMC8926152
OpenAlexW3010352845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.