ArticleScientific reports2020
The association between fear extinction, the ability to accomplish exposure and exposure therapy outcome in specific phobia.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Frontopolar multifocal transcranial direct current stimulation reduces conditioned fear reactivity during extinction training: A pilot randomized controlled trial.Neurobiology of learning and memory · 2023Trial
- Do oral contraceptives modulate the effects of stress induction on one-session exposure efficacy and generalization in women?Psychopharmacology · 2023Trial
- Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies.Depression and anxiety · 2022Trial
- A ventral striatal learning signal reflecting individual differences in the success of fear extinction.Molecular psychiatry · 2026Article
- Learning, sleep replay and consolidation of contextual fear memories: A neural network model.PLoS computational biology · 2026Article
- Trajectory of severe COVID anxiety and predictors for recovery in an 18-month UK cohort.BJPsych open · 2025Article
- A visual generalization gradient of conceptual stimuli based on fear acquisition in visual and auditory modalities.NPJ science of learning · 2025Article
- Extinction context is learned by pigeons, not given by the environment.Communications psychology · 2025Article
- A microglial compliment: controlling neuronal function from within.Signal transduction and targeted therapy · 2024Article
- The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity.Molecular psychiatry · 2024Article
- Using pre-treatment de novo threat conditioning outcomes to predict treatment response to DCS augmentation of exposure-based CBT.Journal of psychiatric research · 2023Article
- Is Fear Extinction Impairment Central to Psychopathology?Current topics in behavioral neurosciences · 2023Article
- Understanding clinical fear and anxiety through the lens of human fear conditioning.Nature reviews psychology · 2023Review
- COBMC psychiatry · 2022Article
- Recognition memory, primacy vs. recency effects, and time perception in the online version of the fear of scream paradigm.Scientific reports · 2022Article
- Skin conductance levels and responses in Asian and White participants during fear conditioningPhysiology & behavior · 2022Article
- Combined Fainting and Psychogenic Non-epileptic Seizures as Significant Therapy Hurdles in Blood-Injury-Injection Phobia: A Mini-Review and Case Report.Frontiers in psychiatry · 2022Article
- Vagus Nerve Stimulation as a Treatment for Fear and Anxiety in Individuals with Autism Spectrum Disorder.Journal of psychiatry and brain science · 2022Article
- Strategies to improve access to cognitive behavioral therapies for anxiety disorders: A scoping review.PloS one · 2022Article
- Conscious knowledge of CS-UCS contingency information affects extinction retrieval of conditioned disgust responses: Findings from an online de novo disgust conditioning task.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Great interest exists in maximizing exposure therapy efficacy in anxiety disorders. At the same time, reduced frequency and shortened duration of exposure sessions are required to meet the specific regularities in routine care settings. Extinction has emerged as the key mechanism of exposure treatment in anxiety disorders. Examining exposure treatment processes from the perspective of extinction learning might provide novel insights into variability in exposure treatment duration and outcome. The present study sought to examine the functional link between fear extinction, the ability to accomplish exposure in a predetermined time and exposure therapy outcome in specific phobia. Treatment-seeking individuals (N = 53) with spider phobia underwent a context-dependent fear conditioning paradigm prior to a standardized exposure. Spider-phobic participants who were able to complete exposure within the pre-determined time (i.e., completers) showed a more pronounced short- and long-term exposure therapy benefit. In the fear conditioning task, a more pronounced decline in CS-US contingency ratings during extinction (retrieval) was found in completers relative to non-completers. The failure to further extinguish US expectancy to the CSs in non-completers might offer a potential mechanistic explanation why non-completers have difficulties to accomplish all exposure steps in a fixed time and show less pronounced treatment gains. Our findings bear specific implications for the implementation of exposure treatment to routine care settings.
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