ArticleScientific reports2020
Functional switching of NPR1 between chloroplast and nucleus for adaptive response to salt stress.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- CbLTP67 Negatively Regulates Salt Tolerance by Interaction With CbPAT12 and CbRD19A to Disrupt Salicylic Acid-Mediated Stomatal Closure in Catalpa bungei.Plant, cell & environment · 2026Article
- Plant BTB (Broad-Complex, Tramtrack, and Bric-à-Brac) Proteins: Structural Features, Biological Functions, and Roles in Stress Responses.Plants (Basel, Switzerland) · 2026Review
- Salicylic acid enhances photosynthesis in Borago officinalis plants exposed to water deficit by nitric oxide-mediated boosting carbonic anhydrase and antioxidant system.BMC plant biology · 2025Article
- NPR1 suppresses Candidatus Liberibacter asiaticus-induced callose and reactive oxygen species accumulation.Plant physiology · 2025Article
- Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade.Molecular plant · 2024Article
- Cadmium toxicity promotes hormonal imbalance and induces the expression of genes involved in systemic resistances in barley.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024Article
- Mechanisms by Which Exogenous Substances Enhance Plant Salt Tolerance through the Modulation of Ion Membrane Transport and Reactive Oxygen Species Metabolism.Antioxidants (Basel, Switzerland) · 2024Review
- Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade.bioRxiv : the preprint server for biology · 2024Article
- NPR1 Translocation from Chloroplast to Nucleus Activates Plant Tolerance to Salt Stress.Antioxidants (Basel, Switzerland) · 2023Article
- Emerging Roles of Salicylic Acid in Plant Saline Stress Tolerance.International journal of molecular sciences · 2023Review
- Photosynthetic machinery under salinity stress: Trepidations and adaptive mechanisms.Photosynthetica · 2023Review
- TGA transcription factors-Structural characteristics as basis for functional variability.Frontiers in plant science · 2022Review
- Phytosphingosine induces systemic acquired resistance through activation of sphingosine kinase.Plant direct · 2021Article
- Physiological and Molecular Responses of Six Apple Rootstocks to Osmotic Stress.International journal of molecular sciences · 2021Article
- De novo transcriptome sequencing and analysis of salt-, alkali-, and drought-responsive genes in Sophora alopecuroides.BMC genomics · 2020Article
- miRNA-mRNA Analysis Reveals That Alfalfa Responds to Saline-Alkali Stress via Phenylpropanoid Biosynthesis and Starch and Sucrose Metabolism Pathways.Physiologia plantarumArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salt stress causes rapid accumulation of nonexpressor of pathogenesis-related genes 1 (NPR1) protein, known as the redox-sensitive transcription coactivator, which in turn elicits many adaptive responses. The NPR1 protein transiently accumulates in chloroplast stroma under salt stress, which attenuates stress-triggered down-regulation of photosynthetic capability. We observed that oligomeric NPR1 in chloroplasts and cytoplasm had chaperone activity, whereas monomeric NPR1 in the nucleus did not. Additionally, NPR1 overexpression resulted in reinforcement of morning-phased and evening-phased circadian clock. NPR1 overexpression also enhanced antioxidant activity and reduced stress-induced reactive oxygen species (ROS) generation at early stage, followed with transcription levels for ROS detoxification. These results suggest a functional switch from a molecular chaperone to a transcriptional coactivator, which is dependent on subcellular localization. Our findings imply that dual localization of NPR1 is related to proteostasis and redox homeostasis in chloroplasts for emergency restoration as well as transcriptional coactivator in the nucleus for adaptation to stress.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.