Evidence map›Paper›PMID 32152389›Full record

ArticleThe ISME journal2020

Bacterial vitamin B

Nermin Akduman, James W Lightfoot, Waltraud Röseler, Hanh Witte, Wen-Sui Lo, Christian Rödelsperger, Ralf J Sommer

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The ISME journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 62 citations in OpenAlex.

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  9. bioRxiv : the preprint server for biology · 2025
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  12. High Nutritional Conditions Influence Feeding Plasticity in Pristionchus pacificus and Render Worms Non-Predatory.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025
    Article
  13. Article
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  15. Review
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  19. Vitamin BNature cell biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nermin AkdumanDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.
James W LightfootDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.
Waltraud RöselerDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.
Hanh WitteDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.
Wen-Sui LoDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.
Christian RödelspergerDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany.ORCID http://orcid.org/0000-0002-7905-9675
Ralf J SommerDepartment for Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Ring 9, 72076, Tübingen, Germany. ralf.sommer@tuebingen.mpg.de.ORCID http://orcid.org/0000-0003-1503-7749
Max Planck Institute for Developmental Biology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the microbiota is known to affect host development, metabolism, and immunity, its impact on host behavior is only beginning to be understood. In order to better characterize behavior modulation by host-associated microorganisms, we investigated how bacteria modulate complex behaviors in the nematode model organism Pristionchus pacificus. This nematode is a predator that feeds on the larvae of other nematodes, including Caenorhabditis elegans. By growing P. pacificus on different bacteria and testing their ability to kill C. elegans, we reveal large differences in killing efficiencies, with a Novosphingobium species showing the strongest enhancement. This enhanced killing was not accompanied by an increase in feeding, which is a phenomenon known as surplus killing, whereby predators kill more prey than necessary for sustenance. Our RNA-seq data demonstrate widespread metabolic rewiring upon exposure to Novosphingobium, which facilitated screening of bacterial mutants with altered transcriptional responses. We identified bacterial production of vitamin B

Indexed as

AnimalsBacteriaCaenorhabditis elegansMicrobiotaNematodaPredatory BehaviorVitamin B 12VitaminsVitamin B 12Vitamins

Identifiers

PMID32152389
PMCPMC7242318
OpenAlexW3010237883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.