Evidence map›Paper›PMID 32152196›Full record

ArticleInfection and immunity2020

Fluorescence-Reported Allelic Exchange Mutagenesis-Mediated Gene Deletion Indicates a Requirement for Chlamydia trachomatis Tarp during

Susmita Ghosh, Elizabeth A Ruelke, Joshua C Ferrell, Maria D Bodero, Kenneth A Fields, Travis J Jewett

Abstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. ThemBio · 2026
    Article
  2. Review
  3. Article
  4. ThebioRxiv : the preprint server for biology · 2025
    Article
  5. The N-terminus of theMicrobiology spectrum · 2025
    Article
  6. Chlamydia trachomatis invasion: a duet of effectors.Biochemical Society transactions · 2025
    Review
  7. Journal of bacteriology · 2025
    Review
  8. Article
  9. Article
  10. The N-terminus of thebioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Dynamin-dependent entry ofResearch square · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Plasmid-mediated virulence inFrontiers in cellular and infection microbiology · 2023
    Review
  17. Advances in genetic manipulation ofFrontiers in immunology · 2023
    Review
  18. Molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2023
    Review
  19. Review
  20. Frontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susmita GhoshDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Elizabeth A RuelkeDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA.
Joshua C FerrellDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Maria D BoderoDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Kenneth A FieldsDepartment of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Travis J JewettDivision of Immunity and Pathogenesis, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, USA travis.jewett@ucf.edu.

Funding

Type III exported effectors of Chlamydia trachomatisR01AI065530 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FIELDS, KENNETH A · 2005 to 2021
$5.7M
Molecular Analysis of the Chlamydia trachomatis virulence factor TarpR01AI139242 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI JEWETT, TRAVIS JAMES · 2019 to 2022
$2.3M
Mutagenesis in Chlamydia trachomatis via allelic exchangeR21AI124649 · NIAID · UNIVERSITY OF KENTUCKY · PI FIELDS, KENNETH A · 2016 to 2017
$409k
NIAID NIH HHS R01 AI065530NIAID NIH HHS R01 AI139242NIAID NIH HHS R21 AI124649
6 · The paper itself

Abstract

The translocated actin recruiting phosphoprotein (Tarp) is a multidomain type III secreted effector used by

Indexed as

ActinsAllelesAnimalsBacterial ProteinsCell Line, TumorChlamydia InfectionsChlamydia trachomatisFluorescenceGene DeletionHeLa CellsHumansMiceMice, Inbred C3HMutagenesisPhosphoproteinsVirulenceActinsBacterial ProteinsPhosphoproteinsactinactin cytoskeletonChlamydia trachomatiscytoskeletoneffectoreffector functionsTarp

Identifiers

PMID32152196
PMCPMC7171248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.