Evidence map›Paper›PMID 32152189›Full record

ArticleThe Plant cell2020

Critical Role of Transcript Cleavage in Arabidopsis RNA Polymerase II Transcriptional Elongation.

Wojciech Antosz, Jules Deforges, Kevin Begcy, Astrid Bruckmann, Yves Poirier, Thomas Dresselhaus, Klaus D Grasser

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  8. Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.International journal of biological macromolecules · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Distinct role of subunits of theFrontiers in plant science · 2022
    Article
  14. Review
  15. Global Run-on Sequencing (GRO-Seq).Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Wojciech AntoszDepartment of Cell Biology & Plant Biochemistry, Biochemistry Centre, University of Regensburg, D-93040 Regensburg, Germany.ORCID 0000-0001-9127-8267
Jules DeforgesDepartment of Plant Molecular Biology, University of Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0002-8914-1218
Kevin BegcyEnvironmental Horticulture Department, University of Florida, Gainesville, Florida 32611.ORCID 0000-0002-5046-8029
Astrid BruckmannDepartment for Biochemistry I, Biochemistry Centre, University of Regensburg, D-93040 Regensburg, Germany.ORCID 0000-0001-6082-2944
Yves PoirierDepartment of Plant Molecular Biology, University of Lausanne, CH-1015 Lausanne, Switzerland.ORCID 0000-0001-8660-294X
Thomas DresselhausDepartment of Cell Biology & Plant Biochemistry, Biochemistry Centre, University of Regensburg, D-93040 Regensburg, Germany.ORCID 0000-0001-6442-4302
Klaus D GrasserDepartment of Cell Biology & Plant Biochemistry, Biochemistry Centre, University of Regensburg, D-93040 Regensburg, Germany klaus.grasser@ur.de.ORCID 0000-0002-7080-5520
University of Regensburg · DEUniversity of Lausanne · CHUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcript elongation factors associate with elongating RNA polymerase II (RNAPII) to control the efficiency of mRNA synthesis and consequently modulate plant growth and development. Encountering obstacles during transcription such as nucleosomes or particular DNA sequences may cause backtracking and transcriptional arrest of RNAPII. The elongation factor TFIIS stimulates the intrinsic transcript cleavage activity of the polymerase, which is required for efficient rescue of backtracked/arrested RNAPII. A TFIIS mutant variant (TFIISmut) lacks the stimulatory activity to promote RNA cleavage, but instead efficiently inhibits unstimulated transcript cleavage by RNAPII. We could not recover viable Arabidopsis (

Indexed as

Transcription Elongation, GeneticAmino Acid SequenceArabidopsisCell NucleusCell ProliferationMutant ProteinsPlant RootsProteasome Endopeptidase ComplexProteolysisRNA, MessengerRNA Polymerase IITranscriptional Elongation FactorsTranscription, GeneticTranscriptomeMutant ProteinsProteasome Endopeptidase ComplexRNA, MessengerRNA Polymerase IITranscriptional Elongation Factorstranscription factor S-II

Identifiers

PMID32152189
PMCPMC7203918
OpenAlexW3010690180

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.