Evidence map›Paper›PMID 32152180›Full record

ArticleDisease models & mechanisms2020

Zika virus non-structural protein NS4A restricts eye growth in

Sneh Harsh, Yulong Fu, Eric Kenney, Zhe Han, Ioannis Eleftherianos

Open access · goldAbstract read
In one paragraph

Article in Disease models & mechanisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  5. Article
  6. Frontiers in microbiology · 2024
    Article
  7. Article
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  9. Review
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  19. International journal of molecular sciences · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sneh HarshDepartment of Biological Sciences, The George Washington University, Washington, DC 20052, USA.
Yulong FuCenter for Genetic Medicine Research, Children's National Health System. Department of Genomics and Precision Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.
Eric KenneyDepartment of Biological Sciences, The George Washington University, Washington, DC 20052, USA.
Zhe HanCenter for Genetic Medicine Research, Children's National Health System. Department of Genomics and Precision Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.
Ioannis EleftherianosDepartment of Biological Sciences, The George Washington University, Washington, DC 20052, USA ioannise@gwu.edu.ORCID 0000-0002-4822-3110
George Washington University · USChildren's National · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Role of TGF-beta signaling in the Drosophila immune response against nematode-bacteria complexesR01AI110675 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI ELEFTHERIANOS, IOANNIS · 2015 to 2018
$954k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NIAID NIH HHS R01 AI110675
6 · The paper itself

Abstract

To gain a comprehensive view of the changes in host gene expression underlying Zika virus (ZIKV) pathogenesis, we performed whole-genome RNA sequencing (RNA-seq) of ZIKV-infected

Indexed as

Signal TransductionAnimalsApoptosisCell ProliferationDown-RegulationDrosophila melanogasterDrosophila ProteinsEpitheliumEyeGene Expression ProfilingGene Expression Regulation, DevelopmentalJanus KinasesLarvaOrgan SizePhenotypeReceptors, NotchDrosophila ProteinsJanus KinasesReceptors, NotchSTAT Transcription FactorsViral Nonstructural ProteinsDrosophilaEye developmentHost-pathogen interactionJAK/STAT signalingZika virus

Identifiers

PMID32152180
PMCPMC7197722
OpenAlexW3010007401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.