Evidence map›Paper›PMID 32152125›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Lysosomal degradation products induce

Patrice Newton, David R Thomas, Shawna C O Reed, Nicole Lau, Bangyan Xu, Sze Ying Ong, Shivani Pasricha, Piyush B Madhamshettiwar, Laura E Edgington-Mitchell, Kaylene J Simpson and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Quantitative three-dimensional imaging ofInfection and immunity · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Multiple spacer sequence typing ofFrontiers in veterinary science · 2024
    Article
  12. Article
  13. Article
  14. Archives of Razi Institute · 2023
    Review
  15. Article
  16. Article
  17. Identification of essential genes inMicrobial genomics · 2023
    Article
  18. MicroRNAs Contribute to Host Response toInfection and immunity · 2023
    Article
  19. Establishing the intracellular niche of obligate intracellular vacuolar pathogens.Frontiers in cellular and infection microbiology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Patrice NewtonDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia.
David R ThomasDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia.
Shawna C O ReedDepartment of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven CT 06510.
Nicole LauDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia.
Bangyan XuDepartment of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3052, Australia.
Sze Ying OngCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC 3168 Australia.
Shivani PasrichaCentre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC 3168 Australia.
Piyush B MadhamshettiwarVictorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Laura E Edgington-MitchellDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Kaylene J SimpsonVictorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Craig R RoyDepartment of Microbial Pathogenesis, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven CT 06510.
Hayley J NewtonDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3000, Australia; hnewton@unimelb.edu.au.ORCID 0000-0002-9240-2001
The University of Melbourne · AUHudson Institute of Medical Research · AUYale University · USCenter for Clinical Research (United States) · USPeter MacCallum Cancer Centre · AU

Funding

Biogenesis of the Coxiella-containing vacuoleR01AI114760 · NIAID · YALE UNIVERSITY · PI ROY, CRAIG R. · 2015 to 2019
$2.1M
NIAID NIH HHS R01 AI114760
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Host-Pathogen InteractionsBacterial ProteinsBacterial Secretion SystemsCoxiella burnetiiGene Expression Regulation, BacterialHeLa CellsHumansLysosomesProtein TransportQ FeverTripeptidyl-Peptidase 1VirulenceBacterial ProteinsBacterial Secretion SystemsTPP1 protein, humanTripeptidyl-Peptidase 1amino acid sensingCoxiella burnetiiDot/Icm secretion systemsiRNA screenvirulence regulation

Identifiers

PMID32152125
PMCPMC7104363
OpenAlexW3009609838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.