Evidence map›Paper›PMID 32152015›Full record

ArticleAnnals of family medicine2020

Predicting Opioid Use Following Discharge After Cesarean Delivery.

Jacqueline A Carrico, Katharine Mahoney, Kristen M Raymond, Shannon K McWilliams, Lena M Mayes, Susan K Mikulich-Gilbertson, Karsten Bartels

2 registry-linked trialsOpen access · diamondAbstract read
In one paragraph

Article in Annals of family medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03034278 completednot on this map

Improving Opioid Prescription Safety After Surgery

TypeobservationalSponsorUniversity of Colorado, DenverRan2017 to 2021Enrolled785ConditionsOpioid UseArmsNot applicable - no intervention
NCT05221866 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficiency And Quality In Post-Surgical Pain Therapy After Discharge

TypeinterventionalSponsorUniversity of NebraskaRan2022 to 2023Enrolled711ConditionsOpioid Use, Opioid Dependence, Opioid Misuse, Post-Surgical ComplicationArmsEmpowering Patient to Steer Their Pain Management After Surgery, Provider-facing Prescription Aid
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. PostRegional anesthesia and pain medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jacqueline A CarricoDepartment of Anesthesiology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Katharine MahoneyDepartment of Anesthesiology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Kristen M RaymondDepartment of Psychiatry, Division of Substance Dependence, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Shannon K McWilliamsDepartment of Psychiatry, Division of Substance Dependence, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Lena M MayesDepartment of Anesthesiology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Susan K Mikulich-GilbertsonDepartment of Psychiatry, Division of Substance Dependence, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
Karsten BartelsDepartment of Anesthesiology, University of Colorado, Anschutz Medical Campus, Aurora, Colorado karsten.bartels@ucdenver.edu.
University of Colorado Anschutz Medical Campus · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Improving Opioid Prescription Safety After SurgeryK23DA040923 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BARTELS, KARSTEN · 2016 to 2020
$945k
NCATS NIH HHS UL1 TR002535NIDA NIH HHS K23 DA040923
6 · The paper itself

Abstract

purposeAlthough cesarean delivery is the most common surgical procedure in the United States, postoperative opioid prescribing varies greatly. We hypothesized that patient characteristics, procedural characteristics, or both would be associated with high vs low opioid use after discharge. This information could help individualize prescriptions.

methodsIn this prospective cohort study, we quantified opioid use for 4 weeks following hospital discharge after cesarean delivery. Predischarge characteristics were obtained from health records, and patients self-reported total opioid use postdischarge on weekly questionnaires. Opioid use was quantified in milligram morphine equivalents (MMEs). Binomial and Poisson regression analyses were performed to assess predictors of opioid use after discharge.

resultsOf the 233 patients starting the study, 203 (87.1%) completed at least 1 questionnaire and were included in analyses (86.3% completed all 4 questionnaires). A total of 113 patients were high users (>75 MMEs) and 90 patients were low users (≤75 MMEs) of opioids postdischarge. The group reporting low opioid use received on average 44% fewer opioids in the 24 hours before discharge compared with the group reporting high opioid use (mean = 33.0 vs 59.3 MMEs,

conclusionsKnowledge of predischarge opioid use can be useful as a tool to inform individualized opioid prescriptions, help optimize nonopioid analgesia, and reduce opioid use. Additional studies are needed to evaluate the impact of implementing such measures on prescribing practices, pain, and functional outcomes.

Indexed as

Cesarean SectionAdultAnalgesics, OpioidColoradoFemaleHumansPain MeasurementPatient DischargePostnatal CarePostoperative PainPractice Patterns, Physicians'PregnancyProspective StudiesRegression AnalysisAnalgesics, Opioidanalgesiaanalgesicscesarean sectioncontrolled substancesnon-narcoticobstetricalopioidspainpain managementpostoperativepractice-based research

Identifiers

PMID32152015
PMCPMC7062496
OpenAlexW3010277162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.