Evidence map›Paper›PMID 32150908›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in

James Cobley, Anna Noble, Rachel Bessell, Matthew Guille, Holger Husi

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  2. Ten "Cheat Codes" for Measuring Oxidative Stress in Humans.Antioxidants (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

James CobleyCentre for Health Sciences, University of the Highlands and Islands, Inverness IV2 3JH, UK.
Anna NobleSchool of Biological Sciences, European Xenopus Resource Centre, University of Portsmouth, King Henry Building, Portsmouth PO1 2DY, UK.
Rachel BessellCentre for Health Sciences, University of the Highlands and Islands, Inverness IV2 3JH, UK.
Matthew GuilleSchool of Biological Sciences, European Xenopus Resource Centre, University of Portsmouth, King Henry Building, Portsmouth PO1 2DY, UK.
Holger HusiCentre for Health Sciences, University of the Highlands and Islands, Inverness IV2 3JH, UK.
University of the Highlands and Islands · GBUniversity of Portsmouth · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R014841/1Highlands and Islands Enterpise HMS 9353763Wellcome Trust 212942/Z/18/Z
6 · The paper itself

Abstract

Oocytes are postulated to repress the proton pumps (e.g., complex IV) and ATP synthase to safeguard mitochondrial DNA homoplasmy by curtailing superoxide production. Whether the ATP synthase is inhibited is, however, unknown. Here we show that: oligomycin sensitive ATP synthase activity is significantly greater (~170 vs. 20 nmol/min

Indexed as

ATP synthaseclick chemistrymitochondriaoocyteredox signalingthiolXenopus laevis

Identifiers

PMID32150908
PMCPMC7139892
OpenAlexW3010637888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.