ArticleMaterials (Basel, Switzerland)2020
Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Morphological and Cytotoxic Effects of Metal Salts on Osteoblast Cells in Three-Dimensional Spheroidal Cultures.Journal of toxicology · 2026Article
- N-Doped Graphene for Biomedical Applications: A Comparative Biocompatibility Assessment of Green and Chemical Exfoliation.Chemical research in toxicology · 2025Article
- Impact of Metal Ions on Cellular Functions: A Focus on Mesenchymal Stem/Stromal Cell Differentiation.International journal of molecular sciences · 2024Review
- Survivability of Titanium Implant Materials: In Vitro Simulated Inflammatory and Infectious Environment.Annals of biomedical engineering · 2023Article
- Corrosion Products from Metallic Implants Induce ROS and Cell Death in Human MotoneuronsJournal of functional biomaterials · 2023Article
- Does Green Exfoliation of Graphene Produce More Biocompatible Structures?Pharmaceutics · 2023Article
- Experimental Investigation of Material Transfer on Bearings for Total Hip Arthroplasty-A Retrieval Study on Ceramic and Metallic Femoral Heads.Journal of clinical medicine · 2022Article
- Effect of the Size of Titanium Particles Released from Dental Implants on Immunological Response.International journal of molecular sciences · 2022Article
- Influence of CuInternational journal of molecular sciences · 2021Article
- The Role of Metal Ions in Biology, Biochemistry and Medicine.Materials (Basel, Switzerland) · 2021Article
- Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro.Nanomaterials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Monocytes and macrophages are the first barrier of the innate immune system, which interact with abrasion and corrosion products, leading to the release of proinflammatory mediators and free reactive molecules. The aim of this study was to understand inflammation-relevant changes in monocytes and macrophages after exposure to corrosion products. To do this, the THP-1 cell line was used to analyze the effects of metal ions simultaneously in monocytes and differentiated macrophages. Cells were stimulated with several concentrations of metal salts (CoCl
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.