Evidence map›Paper›PMID 32150662›Full record

ArticleJournal of cellular and molecular medicine2020

Adenosine-5'-triphosphate suppresses proliferation and migration capacity of human endometrial stem cells.

Svetlana Semenova, Alla Shatrova, Irina Vassilieva, Margarita Shamatova, Natalja Pugovkina, Yuri Negulyaev

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Store-Operated CaInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Svetlana SemenovaInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.ORCID 0000-0002-3537-2459
Alla ShatrovaInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.
Irina VassilievaInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.
Margarita ShamatovaInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.
Natalja PugovkinaInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.
Yuri NegulyaevInstitute of Cytology of the Russian Academy of Science, Saint-Petersburg, Russia.
Institute of Cytology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular ATP through the activation of the P2X and P2Y purinergic receptors affects the migration, proliferation and differentiation of many types of cells, including stem cells. High plasticity, low immunogenicity and immunomodulation ability of mesenchymal stem cells derived from human endometrium (eMSCs) allow them to be considered a prominent tool for regenerative medicine. Here, we examined the role of ATP in the proliferation and migration of human eMSCs. Using a wound healing assay, we showed that ATP-induced activation of purinergic receptors suppressed the migration ability of eMSCs. We found the expression of one of the ATP receptors, the P2X

Indexed as

AdamantaneAdenosine TriphosphateAminoquinolinesCell MovementCell ProliferationEndometriumFemaleGene Expression Regulation, DevelopmentalHumansMesenchymal Stem CellsPurinergic P2X Receptor AgonistsPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X7Receptors, Purinergic P2YRegeneration3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphateAdamantaneAdenosine TriphosphateAminoquinolinesAZ10606120Purinergic P2X Receptor AgonistsPurinergic P2X Receptor AntagonistsReceptors, Purinergic P2X7Receptors, Purinergic P2YCa2+ influxcell cyclecell migrationendometrial stem cellsextracellular ATPreceptor P2X7

Identifiers

PMID32150662
PMCPMC7176887
OpenAlexW3009397166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.