ArticleBlood advances2020
Monoallelic loss-of-function THPO variants cause heritable thrombocytopenia.
Article in Blood advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- α-Actinin-1 in Megakaryocytes: Its Structure, Interacting Proteins and Implications for Thrombopoiesis.Biomedicines · 2025Review
- Article
- Article
- Decitabine facilitates thrombopoiesis independent of the thrombopoietin receptor in zebrafish.Blood science (Baltimore, Md.) · 2025Article
- A Rare THPO Gene Mutation in a Saudi Female Child: A Case Report and Literature Review.Cureus · 2024Article
- Article
- Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.Cell · 2023Article
- Defective binding of ETS1 and STAT4 due to a mutation in the promoter region ofHaematologica · 2023Article
- Genomic legacy of migration in endangered caribou.PLoS genetics · 2022Article
- Novel THPO variant in hereditary thrombocytopenia: A potential candidate variant for predisposition to myeloid neoplasm.PloS one · 2022Article
- The thrombopoietin receptor: revisiting the master regulator of platelet production.Platelets · 2021Review
- Inherited Platelet Disorders: An Updated Overview.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.