ArticlePloS one2020
Integrated analysis of the transcriptome and metabolome of purple and green leaves of Tetrastigma hemsleyanum reveals gene expression patterns involved in anthocyanin biosynthesis.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 39 citations in OpenAlex.
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- Diversity of organ-specific plant transcriptomes.Acta biochimica Polonica · 2025Review
- Metabolomics and transcriptomics combined with physiology reveal key metabolic pathway responses in tobacco roots exposed to NaHS.BMC plant biology · 2024Article
- Variability of plant transcriptomic responses under stress acclimation: a review from high throughput studies.Acta biochimica Polonica · 2024Review
- Insights into Metabolic Engineering of Bioactive Molecules inCurrent genomics · 2023Review
- Genome-Wide Identification of Bilberry WRKY Transcription Factors: Go Wild and Duplicate.Plants (Basel, Switzerland) · 2023Article
- Transcription-associated metabolomic profiling reveals the critical role of frost tolerance in wheat.BMC plant biology · 2022Article
- Integration of metabolomics and transcriptomics data to further characterize Gliricidia sepium (Jacq.) Kunth under high salinity stress.The plant genome · 2022Article
- Upcoming progress of transcriptomics studies on plants: An overview.Frontiers in plant science · 2022Review
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- Gene-Metabolite Network Analysis Revealed Tissue-Specific Accumulation of Therapeutic Metabolites inInternational journal of molecular sciences · 2021Article
- Transcriptome and Metabolome Integrated Analysis of Two Ecotypes ofPlants (Basel, Switzerland) · 2021Article
- Transcriptomics Integrated With Widely Targeted Metabolomics Reveals the Mechanism Underlying Grain Color Formation in Wheat at the Grain-Filling Stage.Frontiers in plant science · 2021Article
- Research Progress and Future Development Trends in Medicinal Plant Transcriptomics.Frontiers in plant science · 2021Review
- Seasonal Variation in Transcriptomic Profiling ofFrontiers in plant science · 2021Article
- Cross-Talk Between Intestinal Microbiota and Host Gene Expression in Gilthead Sea Bream (Frontiers in physiology · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To gain better insight into the regulatory networks of anthocyanin biosynthesis, an integrated analysis of the metabolome and transcriptome in purple and green leaves of Tetrastigma hemsleyanum was conducted. Transcript and metabolite profiles were archived by RNA-sequencing data analysis and LC-ESI-MS/MS, respectively. There were 209 metabolites and 4211 transcripts that were differentially expressed between purple and green leaves. Correlation tests of anthocyanin contents and transcriptional changes showed 141 significant correlations (Pearson correlation coefficient >0.8) between 16 compounds and 14 transcripts involved in the anthocyanin biosynthesis pathway. Some novel genes and metabolites were discovered as potential candidate targets for the improvement of anthocyanin content and superior cultivars.
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