Evidence map›Paper›PMID 32150558›Full record

ArticlePLoS neglected tropical diseases2020

Transmission center and driving factors of hand, foot, and mouth disease in China: A combined analysis.

Yi Hu, Lili Xu, Hao Pan, Xun Shi, Yue Chen, Henry Lynn, Shenghua Mao, Huayi Zhang, Hailan Cao, Jun Zhang and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Yi HuDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Lili XuInstitute for Infectious Disease Control and Prevention, Qinghai Provincial Center for Disease Control and Prevention, Qinghai, China.
Hao PanShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Xun ShiDepartment of Geography, Dartmouth College, Hanover, New Hampshire, United States of America.
Yue ChenDepartment of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada.
Henry LynnDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Shenghua MaoShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Huayi ZhangInstitute for Infectious Disease Control and Prevention, Qinghai Provincial Center for Disease Control and Prevention, Qinghai, China.
Hailan CaoInstitute for Infectious Disease Control and Prevention, Qinghai Provincial Center for Disease Control and Prevention, Qinghai, China.
Jun ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Jing ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Shuang XiaoDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Jian HuDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Xiande LiDepartment of Geography, Shanghai Normal University, Shanghai, China.
Shenjun YaoKey Laboratory of Geographic Information Science, Ministry of Education, East China Normal University, Shanghai, China.
Zhijie ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-1276-787X
Genming ZhaoDepartment of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
Ministry of Education of the People's Republic of China · CNShanghai Municipal Center For Disease Control Prevention · CNDartmouth College · USEast China Normal University · CNShanghai Normal University · CNUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hand, foot, and mouth disease (HFMD) has become a major public health issue in China. The disease incidence varies substantially over time and across space. To understand the heterogeneity of HFMD transmission, we compare the spatiotemporal dynamics of HFMD in Qinghai and Shanghai by conducting combined analysis of epidemiological, wavelet time series, and mathematical methods to county-level data from 2009 to 2016. We observe hierarchical epidemic waves in Qinghai, emanating from Huangzhong and in Shanghai from Fengxian. Besides population, we also find that the traveling waves are significantly associated with socio-economic and geographical factors. The population mobility also varies between the two regions: long-distance movement in Qinghai and between-neighbor commuting in Shanghai. Our findings provide important evidence for characterizing the heterogeneity of HFMD transmission and for the design and implementation of interventions, such as deploying optimal vaccine and changing local driving factors in the transmission center, to prevent or limit disease spread in these areas.

Indexed as

Disease Transmission, InfectiousCareer MobilityChildChild, PreschoolChinaFemaleGeographyHand, Foot and Mouth DiseaseHumansIncidenceMaleSocioeconomic FactorsSpatio-Temporal Analysis

Identifiers

PMID32150558
PMCPMC7062235
OpenAlexW3010558587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.