Trial reportPloS one2020
Prospective cohort study on the predictors of fall risk in 119 patients with bilateral vestibulopathy.
Trial report in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07709143 (The Clinical Trial Protocol), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Clinical Trial Protocol: MRI Performance and Risk Factors of Bilateral Vestibular Hypofunction: A Multi-center Cross-sectional Study
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Pooled it
- Driving ability in patients with dizziness: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Pooled it
- Efficacy of nGVS to improve postural stability in people with bilateral vestibulopathy: A systematic review and meta-analysis.Frontiers in neuroscience · 2022Pooled it
- Vestibular Function Drives Gaze Stability in Locomoting Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The impact of bilateral vestibulopathy on quality of life: data from the Antwerp University Hospital registry.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- The evolution of vestibular function and health-related quality of life in bilateral vestibulopathy.Scientific reports · 2025Article
- Review
- Optimizing vestibular implant electrode positioning using fluoroscopy and intraoperative CT imaging.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- [Recent progress in vestibular prosthesis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Review
- Assessing balance in people with bilateral vestibulopathy using the Mini-Balance Evaluation Systems Test (Mini-BESTest): feasibility and comparison with healthy control data.Journal of neurology · 2023Article
- The impact of vestibular function on cognitive-motor interference: a case-control study on dual-tasking in persons with bilateral vestibulopathy and normal hearing.Scientific reports · 2023Article
- Impact of episodic and chronic vestibular disorders on health-related quality of life and functioning-results from the DizzyReg patient registry.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Altered gait parameters in distracted walking: a bio-evolutionary and prognostic health perspective on passive listening and active responding during cell phone use.Frontiers in integrative neuroscience · 2023Article
- Construct validity and reliability of the Bilateral Vestibulopathy Questionnaire (BVQ).Frontiers in neurology · 2023Article
- Bilateral vestibulopathy: a clinical update and proposed diagnostic algorithm.Frontiers in neurology · 2023Review
- Bilateral vestibulopathy patients' perspectives on vestibular implant treatment: a qualitative study.Journal of neurology · 2022Article
- Patterns of Vestibular Impairment in Bilateral Vestibulopathy and Its Relation to Etiology.Frontiers in neurology · 2022Article
- Development and Content Validity of the Bilateral Vestibulopathy Questionnaire.Frontiers in neurology · 2022Article
- An exploratory investigation on spatiotemporal parameters, margins of stability, and their interaction in bilateral vestibulopathy.Scientific reports · 2021Article
- Paving the Way Toward Distinguishing Fallers From Non-fallers in Bilateral Vestibulopathy: A Wide Pilot Observation.Frontiers in neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify predictive factors for falls in patients with bilateral vestibulopathy (BV). Specific variables contributing to the general work-up of a vestibular patient were compared between BV patients experiencing falls and those who did not.
designProspective multi-centric cohort study.
settingDepartment of Otorhinolaryngology & Head and Neck Surgery at two tertiary referral centers: Antwerp University Hospital and Maastricht University Medical Center.
participantsIn total, 119 BV patients were included. BV diagnosis was defined in accordance with the diagnostic BV criteria, established by the Bárány Society in 2017.
main outcome measuresPatients were divided into fallers and non-fallers, depending on the experience of one or more falls in the preceding 12 months. Residual vestibular function on caloric testing, rotatory chair testing, video head impulse test (vHIT) and cervical vestibular evoked myogenic potentials (cVEMP) was evaluated as a predictive factor for falls. Furthermore, hearing function (speech perception in noise (SPIN)), sound localization performance, etiology, disease duration, sport practice, scores on the Dizziness Handicap Inventory (DHI) and the Oscillopsia Severity Questionnaire (OSQ) were compared between fallers and non-fallers.
resultsForty-five (39%) patients reported falls. In a sub-analysis in the patients recruited at UZA (n = 69), 20% experienced three or more falls and three patients (4%) suffered from severe fall-related injuries. The DHI score and the OSQ score were significantly higher in fallers. Residual vestibular function, SPIN, sound localization performance, etiology, disease duration, age and sport practice did not differ between fallers and non-fallers.
conclusionsFalls and (severe) fall-related injuries are frequent among BV patients. A DHI score > 47 and an OSQ score > 27.5 might be indicative for BV patients at risk for falls, with a sensitivity of 70% and specificity of 60%. Residual vestibular function captured by single vestibular tests (vHIT, calorics, rotatory chair, cVEMP) or by overall vestibular function defined as the number of impaired vestibular sensors are not suitable to distinguish fallers and non-fallers in a BV population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.