Evidence map›Paper›PMID 32150544›Full record

ArticlePLoS neglected tropical diseases2020

Human Plasmodium vivax diversity, population structure and evolutionary origin.

Virginie Rougeron, Eric Elguero, Céline Arnathau, Beatriz Acuña Hidalgo, Patrick Durand, Sandrine Houze, Antoine Berry, Sedigheh Zakeri, Rashidul Haque, Mohammad Shafiul Alam and 20 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

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  6. Genetic Structure of IntroducedTropical medicine and infectious disease · 2024
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  9. Genetic diversity ofEpidemiology and infection · 2023
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  10. Review
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  12. Article
  13. Review
  14. Review
  15. Assessment of antibiotic treatment onFrontiers in microbiology · 2022
    Article
  16. Article
  17. Review
  18. Population genomic evidence ofScience advances · 2021
    Article
  19. Review
  20. Gene Polymorphisms AmongFrontiers in cellular and infection microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 18 institutions in 13 countries.

Virginie RougeronLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.ORCID 0000-0001-5873-5681
Eric ElgueroLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Céline ArnathauLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Beatriz Acuña HidalgoLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Patrick DurandLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Sandrine HouzeService de Parasitologie-mycologie CNR du Paludisme, AP-HP Hôpital Bichat, Paris, France.
Antoine BerryCentre de Physiopathologie de Toulouse-Purpan (CPTP), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1043, CNRS UMR5282, Université de Toulouse Paul Sabatier, F-31300 Toulouse, France.
Sedigheh ZakeriMalaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran.
Rashidul HaqueEmerging Infections & Parasitology Laboratory, icddr,b, Mohakhali, Dhaka, Bangladesh.
Mohammad Shafiul AlamEmerging Infections & Parasitology Laboratory, icddr,b, Mohakhali, Dhaka, Bangladesh.ORCID 0000-0001-8330-5499
François NostenCentre for Tropical Medicine and Global Health,Oxford, United Kingdom.ORCID 0000-0002-7951-0745
Carlo SeveriniDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Tamirat Gebru WoldearegaiInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-9508-1787
Benjamin MordmüllerInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.ORCID 0000-0001-9101-2768
Peter Gottfried KremsnerInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Lilia González-CerónRegional Centre of Research in Public Health, National Institute of Public Health, Tapachula, Chiapas, Mexico.ORCID 0000-0002-2347-5581
Gustavo FontechaMicrobiology Research Institute, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Dionicia GamboaInstituto de Medicina Tropical Alexander Von Humboldt, Universidad Peruana Cayetano Heredia, AP, Lima, Peru.
Lise MussetUnit, Institut Pasteur de Guyane, BP6010, French Guiana.
Eric LegrandMalaria Genetic and Resistance Group, Biology of Host-Parasite Interactions Unit, Institut Pasteur, Paris, France.
Oscar NoyaCentro para Estudios Sobre Malaria, Instituto de Altos Estudios en Salud "Dr. Arnoldo Gabaldón", Ministerio del Poder Popular para la Salud and Instituto de Medicina Tropical, Universidad Central de Venezuela, Maracay, Caracas, Venezuela.
Tepanata PumpaiboolBiomedical Science, Graduate School, Chulalongkorn University, Bangkok, Thailand.
Pingchai HarnyuttanakornMalaria Research Programme, College of Public Health Science, Chulalongkorn University, Bangkok, Thailand.
Khadijetou Mint LekweiryUR-Génomes et milieux, Faculté des Sciences et Techniques, Université de Nouakchott Al-Aasriya, Mauritania.
Musab Mohamad AlbsheerDepartment of Parasitology and Medical Entomology, Medical Campus, University of Khartoum, Sudan.
Muzamil Mahdi Abdel HamidDepartment of Parasitology and Medical Entomology, Medical Campus, University of Khartoum, Sudan.
Ali Ould Mohamed Salem BoukaryUR-Génomes et milieux, Faculté des Sciences et Techniques, Université de Nouakchott Al-Aasriya, Mauritania.
Jean-François TrapeLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
François RenaudLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Franck PrugnolleLaboratoire MIVEGEC (Université de Montpellier-CNRS-IRD), CREES, Montpellier, France.
Centre National de la Recherche Scientifique · FRChulalongkorn University · THInternational Centre for Diarrhoeal Disease Research · BDUniversity of Khartoum · SDAix-Marseille Université · FRAssistance Publique – Hôpitaux de Paris · FRGerman Center for Infection Research · DEHaramaya University · ETInstitut Pasteur · FRInstitut Pasteur de la Guyane · GFIstituto Superiore di Sanità · ITMahidol University · THMinisterio del Poder Popular para la Educación Universitaria, Ciencia y Tecnología · VENational Autonomous University of Honduras · HNPasteur Institute of Iran · IRUniversidad Peruana Cayetano Heredia · PEUniversité de Nouakchott · MRUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than 200 million malaria clinical cases are reported each year due to Plasmodium vivax, the most widespread Plasmodium species in the world. This species has been neglected and understudied for a long time, due to its lower mortality in comparison with Plasmodium falciparum. A renewed interest has emerged in the past decade with the discovery of antimalarial drug resistance and of severe and even fatal human cases. Nonetheless, today there are still significant gaps in our understanding of the population genetics and evolutionary history of P. vivax, particularly because of a lack of genetic data from Africa. To address these gaps, we genotyped 14 microsatellite loci in 834 samples obtained from 28 locations in 20 countries from around the world. We discuss the worldwide population genetic structure and diversity and the evolutionary origin of P. vivax in the world and its introduction into the Americas. This study demonstrates the importance of conducting genome-wide analyses of P. vivax in order to unravel its complex evolutionary history.

Indexed as

Genetic VariationGenotypeGenotyping TechniquesGlobal HealthHumansMalaria, VivaxPlasmodium vivax

Identifiers

PMID32150544
PMCPMC7082039
OpenAlexW3009489858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.