Evidence map›Paper›PMID 32150535›Full record

ArticlePLoS computational biology2020

ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis.

Arshag D Mooradian, Sjoerd van der Post, Kristen M Naegle, Jason M Held

Abstract read
In one paragraph

Article in PLoS computational biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Panomics to decode virulence and fitness in Gram-negative bacteria.Frontiers in cellular and infection microbiology · 2022
    Article
  10. Novel Bioinformatics Strategies Driving Dynamic Metaproteomic Studies.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  11. Review
  12. Review
  13. Metaproteomics Analysis of Host-Microbiota Interfaces.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arshag D MooradianDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.
Sjoerd van der PostDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.ORCID 0000-0002-7965-5311
Kristen M NaegleDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.ORCID 0000-0001-7146-9592
Jason M HeldDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States of America.ORCID 0000-0001-8024-2736

Funding

TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
INVESTIGATING NAPDH OXIDASES AND REDOX SIGNALING IN LUNG CANCER TUMORIGENICITYR01CA200893 · NCI · WASHINGTON UNIVERSITY · PI HELD, JASON M. · 2016 to 2020
$2.1M
OxMRM: A Technique to Quantify Oxidation of Endogenous Redox-Sensitive CysteinesR21CA138308 · NCI · BUCK INSTITUTE FOR RESEARCH ON AGING · PI HELD, JASON M. · 2009 to 2011
$845k
The role of p53 redox-modification in cell fate signalingR21CA179452 · NCI · WASHINGTON UNIVERSITY · PI HELD, JASON M. · 2013 to 2014
$373k
NCI NIH HHS R01 CA200893NCI NIH HHS R21 CA138308NCI NIH HHS R21 CA179452NIGMS NIH HHS T32 GM007067
6 · The paper itself

Abstract

We present ProteoClade, a Python toolkit that performs taxa-specific peptide assignment, protein inference, and quantitation for multi-species proteomics experiments. ProteoClade scales to hundreds of millions of protein sequences, requires minimal computational resources, and is open source, multi-platform, and accessible to non-programmers. We demonstrate its utility for processing quantitative proteomic data derived from patient-derived xenografts and its speed and scalability enable a novel de novo proteomic workflow for complex microbiota samples.

Indexed as

ProteinsSoftwareAnimalsDatabases, ProteinHumansMiceMicrobiotaProteomicsSequence Analysis, ProteinProteins

Identifiers

PMID32150535
PMCPMC7082058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.