Evidence map›Paper›PMID 32150528›Full record

ArticleEmerging infectious diseases2020

Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.

Nisreen M A Okba, Ivy Widjaja, Wentao Li, Corine H GeurtsvanKessel, Elmoubasher A B A Farag, Mohammed Al-Hajri, Wan Beom Park, Myoung-Don Oh, Chantal B E M Reusken, Marion P G Koopmans and 2 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. COVID-19 Diagnosis: Current and Future Techniques.International journal of biological macromolecules · 2021
    Review
  6. Article
  7. COVID and Lung Cancer.Current oncology reports · 2021
    Review
  8. Review
  9. Review
  10. Article
  11. Treatment for emerging viruses: Convalescent plasma and COVID-19.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nisreen M A Okba
Ivy Widjaja
Wentao Li
Corine H GeurtsvanKessel
Elmoubasher A B A Farag
Mohammed Al-Hajri
Wan Beom Park
Myoung-Don Oh
Chantal B E M Reusken
Marion P G Koopmans
Berend-Jan Bosch
Bart L Haagmans

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed and validated 2 species-independent protein-based assays to detect Middle East respiratory syndrome coronavirus functional antibodies that can block virus receptor-binding or sialic acid-attachment. Antibody levels measured in both assays correlated strongly with virus-neutralizing antibody titers, proving their use for serologic confirmatory diagnosis of Middle East respiratory syndrome.

Indexed as

Antibodies, NeutralizingAntibodies, ViralCoronavirus InfectionsEnzyme-Linked Immunosorbent AssayHumansImmunoassayMiddle East Respiratory Syndrome CoronavirusSerologic TestsSpecies SpecificityAntibodies, NeutralizingAntibodies, Viralantibodiesdromedaryhemagglutinationhumanlumazine synthaseMERSMERS-CoVMiddle East respiratory syndromeMiddle East respiratory syndrome coronavirusnanoparticleneutralizationrespiratory infectionsserologyspikeviruseszoonoses

Identifiers

PMID32150528
PMCPMC7181916

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.