ReviewSexually transmitted diseases2020
Otosyphilis: A Review of the Literature.
Review in Sexually transmitted diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 80 citations in OpenAlex.
- Clinical characteristics and diagnostic challenges of otosyphilis in patients with HIV coinfection: a retrospective analysis.AIDS research and therapy · 2026Article
- A Case of Neuro- and Otosyphilis Successfully Managed with a Sequential Regimen Including Ceftriaxone.Infection and drug resistance · 2026Article
- Contemporary Clinical Management of Otosyphilis for Practicing Otolaryngologists-A Scoping Review.The Laryngoscope · 2025Article
- Otosyphilis and Malignant Syphilis in a Human Immunodeficiency Virus-Infected Patient: A Case of Bilateral Hearing Loss with Complete Recovery Following Ceftriaxone Therapy - Case Report.Infection and drug resistance · 2025Article
- Article
- All Eyes and Ears: A Case of Neurosyphilis Presenting With Simultaneous Ocular and Otic Involvement.Cureus · 2024Article
- The great imitator: latent neurosyphilis presenting with uveitis and labyrinthitis.Acta neurologica Belgica · 2023Article
- Otosyphilis as a rare cause of secondary benign paroxysmal positional vertigo: a case report.The Journal of international medical research · 2023Article
- Global, regional, and national trends of syphilis from 1990 to 2019: the 2019 global burden of disease study.BMC public health · 2023Article
- Otosyphilis.Open forum infectious diseases · 2023Article
- Otosyphilis: A rare case of reversible hearing loss in a young man with secondary syphilis.IDCases · 2023Article
- Malignant syphilis in a young woman: A case report.The Journal of international medical research · 2022Article
- Malignant Syphilis in a Female Patient: A Case Report and Mini-Review.Tropical medicine and infectious disease · 2022Article
- Otosyphilis with Clinical and Serologic Responses with Weekly Intramuscular Penicillin: A Case Report and Literature Review.Case reports in infectious diseases · 2022Article
- An Updated Review of Recent Advances in Neurosyphilis.Frontiers in medicine · 2022Review
- A 2021 Update on Syphilis: Taking Stock from Pathogenesis to Vaccines.Pathogens (Basel, Switzerland) · 2021Review
- Article
- Syphilis Manifesting with Unilateral Hearing Loss and Tinnitus.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The number of cases of syphilis has increased in the United States and in many high-income nations. Otosyphilis is a less recognized complication of syphilis that can lead to irreversible sensorineural hearing loss. Different pathophysiological mechanisms have been proposed to explain hearing loss in otosyphilis. We review the literature on otosyphilis in adults and propose the need for future work in this field to identify better ways to diagnose, treat, and manage this disease. Patients with syphilis should be screened routinely for hearing loss, and all patients with new, sudden, or fluctuating sensorineural hearing loss should be evaluated for syphilis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.