Evidence map›Paper›PMID 32149608›Full record

ArticleeLife2020

Bacterial cell cycle control by citrate synthase independent of enzymatic activity.

Matthieu Bergé, Julian Pezzatti, Víctor González-Ruiz, Laurence Degeorges, Geneviève Mottet-Osman, Serge Rudaz, Patrick H Viollier

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Cyclic Isothiocyanate Goitrin ImpairsPlants (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Review
  6. The Replicative DnaE Polymerase ofLife (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Matthieu BergéDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-0910-6114
Julian PezzattiInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, Geneva, Switzerland.
Víctor González-RuizInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, Geneva, Switzerland.
Laurence DegeorgesDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Geneviève Mottet-OsmanDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Serge RudazInstitute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, Geneva, Switzerland.
Patrick H ViollierDepartment of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.ORCID 0000-0002-5249-9910
University of Geneva · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_182576
6 · The paper itself

Abstract

Proliferating cells must coordinate central metabolism with the cell cycle. How central energy metabolism regulates bacterial cell cycle functions is not well understood. Our forward genetic selection unearthed the Krebs cycle enzyme citrate synthase (CitA) as a checkpoint regulator controlling the G

Indexed as

Cell Cycle CheckpointsG1 PhaseS PhaseBacterial ProteinsCaulobacter crescentusCitrate (si)-SynthaseCitric Acid CycleDNA Transposable ElementsGene Expression Regulation, BacterialGuanosine PentaphosphateMetabolomeMutagenesis, InsertionalTranscription FactorsBacterial ProteinsCitrate (si)-SynthaseDNA Transposable ElementsGuanosine PentaphosphateTranscription FactorsCaulobacter crescentuscell biologycell developmentcitrate synthaseinfectious diseasemicrobiologymoonlighting enzyme(p)ppGppTCA cycle

Identifiers

PMID32149608
PMCPMC7083601
OpenAlexW2980011286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.