Evidence map›Paper›PMID 32149597›Full record

ArticleThe Journal of general virology2020

A single amino acid in coat protein of Pepper mild mottle virus determines its subcellular localization and the chlorosis symptom on leaves of pepper.

Kelei Han, Hongying Zheng, Mengfei Ji, Weijun Cui, Shuzhen Hu, Jiejun Peng, Jinping Zhao, Yuwen Lu, Lin Lin, Yong Liu and 2 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Kelei HanCollege of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, PR China.
Hongying ZhengState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Mengfei JiState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Weijun CuiState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Shuzhen HuCollege of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, PR China.
Jiejun PengState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Jinping ZhaoKey Laboratory of Biotechnology in Plant Protection of MOA and Zhejiang Province, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, PR China.
Yuwen LuState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Lin LinState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Yong LiuHunan Institute of Plant Protection, Changsha 410125, PR China.
Jianping ChenCollege of Plant Protection, Nanjing Agricultural University, Nanjing, 210095, PR China.
Fei YanState Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, PR China.
Ningbo University · CNNanjing Agricultural University · CNInstitute of Plant Protection · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pepper mild mottle virus (PMMoV) causes serious economic losses in pepper production in China. In a survey for viral diseases on pepper, two PMMoV isolates (named PMMoV-ZJ1 and PMMoV-ZJ2) were identified with different symptoms in Zhejiang province. Sequence alignment analysis suggested there were only four amino acid differences between the isolates: Val262Gly, Ile629Met and Ala1164Thr in the replicase, and Asp20Asn in the coat protein. Infectious cDNA clones of both isolates were constructed and shown to cause distinctive symptoms. Chlorosis symptoms appeared only on PMMoV-ZJ2-infected plants and the Asp20Asn substitution in the CP was shown to be responsible. Confocal assays revealed that the subcellular localization pattern of the two CPs was different, CP

Indexed as

Amino AcidsAmino Acid SequenceCapsicumCapsid ProteinsChinaChloroplastsDNA, ComplementaryGenome, ViralPlant DiseasesPlant LeavesSequence AlignmentTobamovirusVirulenceAmino AcidsCapsid ProteinsDNA, Complementarychlorosiscoat proteinPepper mild mottle virussubcellular localization

Identifiers

PMID32149597
PMCPMC7414450
OpenAlexW3009880522

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.