ArticleJournal of experimental botany2020
The transcription factor MML4_D12 regulates fiber development through interplay with the WD40-repeat protein WDR in cotton.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Genome-wide integrative dissection of genetic basis of fiber color and whiteness regulation in upland cotton (Gossypium hirsutum).BMC biology · 2026Article
- Transcriptional and post-transcriptional regulatory networks controlling cotton fibre development.Plant molecular biology · 2026Review
- Deciphering the dynamic expression network of fiber elongation and the functional role of the GhTUB5 gene for fiber length in cotton based on an introgression population of upland cotton.Journal of advanced research · 2025Article
- GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- TRANSPARENT TESTA 16 collaborates with the MYB-bHLH-WD40 transcriptional complex to produce brown fiber cotton.Plant physiology · 2024Article
- Natural variations in the Cis-elements of GhRPRS1 contributing to petal colour diversity in cotton.Plant biotechnology journal · 2024Article
- RVE2, a new regulatory factor in jasmonic acid pathway, orchestrates resistance to Verticillium wilt.Plant biotechnology journal · 2023Article
- Systematically and Comprehensively Understanding the Regulation of Cotton Fiber Initiation: A Review.Plants (Basel, Switzerland) · 2023Review
- The transcription factor ERF108 interacts with AUXIN RESPONSE FACTORs to mediate cotton fiber secondary cell wall biosynthesis.The Plant cell · 2023Article
- Activation ofPlants (Basel, Switzerland) · 2023Article
- A comprehensive overview of cotton genomics, biotechnology and molecular biological studies.Science China. Life sciences · 2023Review
- Single-cell RNA landscape of the special fiber initiation process in Bombax ceiba.Plant communications · 2023Article
- PnMYB4 negatively modulates saponin biosynthesis inHorticulture research · 2023Article
- Deciphering the complex cotton genome for improving fiber traits and abiotic stress resilience in sustainable agriculture.Molecular biology reports · 2023Review
- Poplar coma morphogenesis and miRNA regulatory networks by combining ovary tissue sectioning and deep sequencing.iScience · 2023Article
- Fine mapping and candidate gene analysis of qFL-A12-5: a fiber length-related QTL introgressed from Gossypium barbadense into Gossypium hirsutum.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Uncovering Hierarchical Regulation among MYB-bHLH-WD40 Proteins and Manipulating Anthocyanin Pigmentation in Rice.International journal of molecular sciences · 2022Article
- Multi-Dimensional Molecular Regulation of Trichome Development inFrontiers in plant science · 2022Review
- Quantitative Trait Locus Analysis and Identification of Candidate Genes for Micronaire in an Interspecific Backcross Inbred Line Population ofFrontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In planta, a vital regulatory complex, MYB-basic helix-loop-helix (bHLH)-WD40 (MBW), is involved in trichome development and synthesis of anthocyanin and proanthocyanin in Arabidopsis. Usually, WD40 proteins provide a scaffold for protein-protein interaction between MYB and bHLH proteins. Members of subgroup 9 of the R2R3 MYB transcription factors, which includes MYBMIXTA-Like (MML) genes important for plant cell differentiation, are unable to interact with bHLH. In this study, we report that a cotton (Gossypium hirsutum) seed trichome or lint fiber-related GhMML factor, GhMML4_D12, interacts with a diverged WD40 protein (GhWDR) in a process similar to but different from that of the MBW ternary complex involved in Arabidopsis trichome development. Amino acids 250-267 of GhMML4_D12 and the first and third WD40 repeat domains of GhWDR determine their interaction. GhWDR could rescue Arabidopsis ttg1 to its wild type, confirming its orthologous function in trichome development. Our findings shed more light towards understanding the key role of the MML and WD40 families in plants and in the improvement of cotton fiber production.
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