Evidence map›Paper›PMID 32149267›Full record

ArticleJBMR plus2020

BMP-Smad Signaling Regulates Postnatal Crown Dentinogenesis in Mouse Molar.

Maiko Omi, Anshul K Kulkarni, Anagha Raichur, Mason Fox, Amber Uptergrove, Honghao Zhang, Yuji Mishina

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  5. [Effects of cell area on single odontoblast polarization and differentiation via microarray technology].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
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  18. USP34 regulates tooth root morphogenesis by stabilizing NFIC.International journal of oral science · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maiko OmiDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.ORCID https://orcid.org/0000-0002-1347-9044
Anshul K KulkarniDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.
Anagha RaichurDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.
Mason FoxDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.
Amber UptergroveDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.
Honghao ZhangDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.
Yuji MishinaDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor MI USA.ORCID https://orcid.org/0000-0002-6268-4204
University of Michigan · US

Funding

Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
Molecular pathogenesis of craniosynostosis caused by enhanced BMP signalingR01DE020843 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MISHINA, YUJI · 2010 to 2019
$4.9M
MicroCT 100S10RR026475 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOHN, DAVID H. · 2010 to 2010
$381k
The function of Hedgehog signaling in maintaining the dental mesenchymal stem cellsR03DE027456 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZHANG, HONGHAO · 2018 to 2019
$312k
NCRR NIH HHS S10 RR026475NIAMS NIH HHS P30 AR069620NIDCR NIH HHS R01 DE020843NIDCR NIH HHS R03 DE027456
6 · The paper itself

Abstract

Dentinogenesis, a formation of dentin by odontoblasts, is an essential process during tooth development. Bone morphogenetic proteins (BMPs) are one of the most crucial growth factors that contribute to dentin formation. However, it is still unclear how BMP signaling pathways regulate postnatal crown and root dentinogenesis. BMPs transduce signals through canonical Smad and non-Smad signaling pathways including p38 and ERK signaling pathways. To investigate the roles of Smad and non-Smad signaling pathways in dentinogenesis, we conditionally deleted

Indexed as

BMPDENTAL MESENCHYMEDENTINDENTINOGENESISODONTOBLAST

Identifiers

PMID32149267
PMCPMC7017888
OpenAlexW2986055335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.