Evidence map›Paper›PMID 32149241›Full record

ArticleACS omega2020

Hyaluronic Acid-Cellulose Composites as Patches for Minimizing Bacterial Infections.

Kelsey M Lopez, Sudhir Ravula, Rocío L Pérez, Caitlan E Ayala, Jack N Losso, Marlene E Janes, Isiah M Warner

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Fluoroquinolone-Based Organic Salts (GUMBOS) with Antibacterial Potential.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Use of a Cellulase fromPharmaceutics · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kelsey M LopezDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Sudhir RavulaDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Rocío L PérezDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Caitlan E AyalaDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Jack N LossoDepartment of Food Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Marlene E JanesDepartment of Food Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Isiah M WarnerDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Louisiana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A facile method was used to synthesize biocomposites containing differing ratios of hyaluronic acid (HA) and cellulose (CEL). Based on the properties of the individual polymers, the resultant composite materials may have potentially great wound care properties. In the method outlined here, 1-butyl-3-methylimidazolium chloride ([Bmim][Cl]), a simple ionic liquid, was used as the sole solvent without chemical modifiers to dissolve the biopolymers at ratios of 1:1 and 2:1 HA to CEL. This method was completely recyclable since the ionic liquid, [Bmim][Cl], can be recovered. Results from spectroscopic measurements [Fourier transform infrared (FT-IR) and X-ray diffraction (XRD)] confirm the interaction between HA and CEL. Scanning electron microscopy (SEM) images reflect differing biopolymer ratios and the resulting impact on the texture and porosity of these composite materials. The composites exhibited high swelling capacity in various media. These composites were also drug-loaded to examine drug release properties for greater potential in combating

Identifiers

PMID32149241
PMCPMC7057694
OpenAlexW3007574886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.