ArticleACS omega2020
Bioactive Effects of Low-Temperature Argon-Oxygen Plasma on a Titanium Implant Surface.
Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Plasma of Argon Treatment of the Implant Surface, Systematic Review of In Vitro Studies.Biomolecules · 2022Pooled it
- Clinical evaluation of cold plasma surface activation using different plasma systems on early implant stability: a randomized controlled within-patient trial.BMC oral health · 2026Trial
- Cold atmospheric plasma for implant surface decontamination and osseointegration: a scoping review with implications for peri-implantitis management.BMC oral health · 2026Article
- The dental implant surface: a review of the past, present and future.Journal of materials science. Materials in medicine · 2026Review
- Comparative Investigation of Vortex and Direct Plasma Discharge for Treating Titanium Surface.Biomimetics (Basel, Switzerland) · 2024Article
- Effect of Silicon Nitride Coating on Titanium Surface: Biocompatibility and Antibacterial Properties.International journal of molecular sciences · 2024Article
- Cold Atmospheric Plasma Improves the Colonization of Titanium with Primary Human Osteoblasts: An In Vitro Study.Biomedicines · 2024Article
- Effect of Low-Temperature Oxygen Plasma Treatment of Titanium Alloy Surface on Tannic Acid Coating Deposition.Materials (Basel, Switzerland) · 2024Article
- Low-Temperature Plasma Techniques in Biomedical Applications and Therapeutics: An Overview.International journal of molecular sciences · 2023Review
- Effects of Argon Gas Plasma Treatment on Biocompatibility of Nanostructured Titanium.International journal of molecular sciences · 2023Article
- An Experimental Anodized and Low-Pressure Oxygen Plasma-Treated Titanium Dental Implant Surface-Preliminary Report.International journal of molecular sciences · 2023Article
- Advances in the superhydrophilicity-modified titanium surfaces with antibacterial and pro-osteogenesis properties: A review.Frontiers in bioengineering and biotechnology · 2022Review
- Kappa-carrageenan-Functionalization of octacalcium phosphate-coated titanium Discs enhances pre-osteoblast behavior and osteogenic differentiation.Frontiers in bioengineering and biotechnology · 2022Article
- Comparison of early osseointegration of non-thermal atmospheric plasma-functionalized/ SLActive titanium implant surfaces in beagle dogs.Frontiers in bioengineering and biotechnology · 2022Article
- Bioactive Coatings on Titanium: A Review on Hydroxylation, Self-Assembled Monolayers (SAMs) and Surface Modification Strategies.Polymers · 2021Review
- Synthesis and Characterization of a Novel Biocompatible Alloy, Ti-Nb-Zr-Ta-Sn.International journal of molecular sciences · 2021Article
- Human osteoblast and fibroblast response to oral implant biomaterials functionalized with non-thermal oxygen plasma.Scientific reports · 2021Article
- Effect of Argon-Based Atmospheric Pressure Plasma Treatment on Hard Tissue Formation on Titanium Surface.International journal of molecular sciences · 2021Article
- Effects of Surface Modification on Adsorption Behavior of Cell and Protein on Titanium Surface by Using Quartz Crystal Microbalance System.Materials (Basel, Switzerland) · 2020Article
- Bioactive Surfaces vs. Conventional Surfaces in Titanium Dental Implants: A Comparative Systematic Review.Journal of clinical medicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although titanium is the most commonly used dental implant material, its biological aging directly leads to a lower rate of osseointegration. The aim of this study is to treat aged titanium disc surfaces using low-temperature argon-oxygen plasma (LTAOP) to obtain a more hydrophilic surface in order to enhance biological activities of osteoblasts on dental implant materials. In this study, smooth-machined titanium (SM Ti) and sandblasted and acid-etched titanium (SLA Ti) substrates were used. Aged titanium discs (SM and SLA Ti) were activated by LTAOP and the surface properties were analyzed. Osteoblasts were then seeded onto the aged and LTAOP-treated surfaces. Cell morphology, viability, and features of osteogenesis were examined. We showed that after the LTAOP treatment, the surfaces of both SM and SLA titanium substrates become more hydrophilic with a larger active oxygen species composition, whereas no obvious morphological changes were observed. Osteoblasts were found to be attached and stretched well on the surfaces of LTAOP treatment specimens. Moreover, the proliferation and osteocalcin secretion of osteoblasts on the plasma-activated titanium samples were superior to the untreated counterparts. LTAOP activation can enhance the attachment, proliferation, and mineralization of osteoblasts on the surfaces of the aged titanium substrates. This research provides a new strategy to modify the surface of titanium dental implants for improved biological functions.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.