ReviewHeliyon2020
A medical mystery of complex regional pain syndrome.
Review in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05745025 (Repeated Transcranial Magnetic Stimulation and Rehabilitation for Individuals With Complex Regional Pain Syndrome Type 1), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Repeated Transcranial Magnetic Stimulation and Rehabilitation for Individuals With Complex Regional Pain Syndrome Type 1
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Pooled it
- Healing from the Inside Out: Vitamins and Nutritional Strategies for Complex Regional Pain Syndrome and Chronic Postsurgical Pain.Current pain and headache reports · 2026Review
- The N13 somatosensory evoked potential in complex regional pain syndrome - A potential marker for central sensitization?Clinical neurophysiology practice · 2026Article
- The Role of Vitamin C Supplementation in Total Knee Arthroplasty Outcomes: A Systematic Review of Randomized Controlled Trials.The archives of bone and joint surgery · 2026Review
- Patients with vitamin D deficiency are more likely to develop complex region pain syndrome after extremity fractures: a large database propensity-matched cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Complex regional pain syndrome and use of psychotropic drugs as a proxy for psychological health.Scientific reports · 2025Article
- Maladaptive Compensatory Neural Mechanisms Associated with Activity-Related Osteoarthritis Pain: Dissociation of Psychological and Activity-Related Neural Mechanisms of WOMAC Pain and VAS Pain.Journal of clinical medicine · 2025Article
- Tetrodotoxin Delivery Pen Safely Uses Potent Natural Neurotoxin to Manage Severe Cutaneous Pain.Advanced healthcare materials · 2025Article
- Article
- Development and validation of a nomogram to predict the risk of post-stroke complex regional pain syndrome.Frontiers in aging neuroscience · 2025Article
- Complex Regional Pain Syndrome: a cross-sectional study of physical symptoms, disability, and psychological health in long term.Pain reports · 2024Article
- The role of fatigue in patients with complex regional pain syndrome.Journal of neurology · 2024Article
- Evidence for converging pathophysiology in complex regional pain-syndrome and primary headache disorders: results from a case-control study.Journal of neurology · 2024Article
- Complex Regional Pain Syndrome after Distal Radius Fracture-Case Report and Mini Literature Review.Journal of clinical medicine · 2024Article
- The Effectiveness of Hyperbaric Oxygen Treatment in Patients with Complex Regional Pain Syndrome: A Retrospective Case series.International journal of medical sciences · 2024Article
- Contact-Heat Evoked Potentials: Insights into Pain Processing in CRPS Type I.Journal of pain research · 2024Article
- Complex Regional Pain Syndrome in Cancer Cases: Current Knowledge and Perspectives.International medical case reports journal · 2024Article
- Efficacy of stellate ganglion interventions for complex regional pain syndrome in the upper limb-A systematic review and meta-analysis.Indian journal of anaesthesia · 2023Review
- A Decade of Complex Regional Pain Syndrome Following Orthopedic Wrist Surgery: A Case Report and a Literature Review.Cureus · 2023Article
- Comparison of Epidemiological Data of Complex Regional Pain Syndrome (CRPS) Patients in Relation to Disease Severity-A Retrospective Single-Center Study.International journal of environmental research and public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complex regional pain syndrome (CRPS) is a condition of neuropathic pain, which is characterized by significant autonomic and inflammatory features. CRPS occurs in patients who have limb surgery, limb fractures, or trauma. Many patients may have pain resolve within twelve months of the inciting incident; however, a small subset progresses to the chronic form. This transitional process often happens by changing from warm CRPS with dominant inflammatory phase to cold CRPS, in which autonomic characteristics or manifestations dominate. Several peripheral and central mechanisms are involved, which might vary among individuals over a period of time. Other contributors include peripheral and central sensitization, autonomic alterations, inflammatory and immune changes, neurochemical changes, and psychological and genetic factors. Although effective management of the chronic CRPS form is often challenging, there are a few high quality randomized controlled trials that support the efficacy of the most commonly used therapeutic approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.