Evidence map›Paper›PMID 32149098›Full record

ArticleBioMed research international2020

The Role of Marine Organic Extract in Bone Regeneration: A Pilot Study.

João César Zielak, Ivana Vendramini, Paola Fernanda Cotait de Lucas Corso, Leonardo Luiz Muller, Viviane Rozeira Crivellaro, Sharukh Soli Khajotia, Fernando Luis Esteban Florez, Rafaela Scariot, Mohammed Elsalanty, Tatiana Miranda Deliberador and 1 more

Abstract read
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In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

João César ZielakSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0003-3393-3491
Ivana VendraminiSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.
Paola Fernanda Cotait de Lucas CorsoSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0003-2428-7387
Leonardo Luiz MullerSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0001-7468-460X
Viviane Rozeira CrivellaroSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.
Sharukh Soli KhajotiaThe University of Oklahoma Health Sciences Center, Department of Restorative Sciences, Division of Dental Biomaterials, College of Dentistry, 1201 N. Stonewall Avenue, Oklahoma City, Oklahoma 73117, USA.
Fernando Luis Esteban FlorezThe University of Oklahoma Health Sciences Center, Department of Restorative Sciences, Division of Dental Biomaterials, College of Dentistry, 1201 N. Stonewall Avenue, Oklahoma City, Oklahoma 73117, USA.ORCID https://orcid.org/0000-0002-8351-0721
Rafaela ScariotSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0002-4911-6413
Mohammed ElsalantyAugusta University, Department of Oral Biology and Diagnostic Sciences, Dental College of Georgia, Augusta, Georgia 30912, USA.
Tatiana Miranda DeliberadorSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0003-4076-4905
Carmen Lucia Mueller StorrerSchool of Health Sciences, Universidade Positivo, Rua Professor Pedro Viriato Parigot de Souza, 5300 Curitiba, Paraná 81280-330, Brazil.ORCID https://orcid.org/0000-0002-1188-8848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel biomaterials capable of accelerating the healing process of skeletal tissues are urgently needed in dentistry. The present in vivo study assessed the osteoconductive and osteoinductive properties of experimental biphasic bioceramics (HA-TCP) modified or not by a nacre extract (marine organic extract, MOE) in a sheep model. Fabrication of MOE involved mixing ground nacre (0.05 g, particle sizes < 0.1 mm) with glacial ethanoic acid (5 mL, pH 7) for 72 hours using external magnetic stirring (25°C). Nonreactive carriers (sterile polythene tubes; 3/animal, radius: 2.5 mm, length: 10.0 mm) pertaining to the control (empty) or experimental groups (HA-TCP or MOE-modified HA-TCP) were implanted intramuscularly into the abdominal segment of the torso in sheep (

Indexed as

Biocompatible MaterialsNacreAnimalsBone RegenerationCeramicsFemaleHydroxyapatitesOsteoblastsOsteoclastsPilot ProjectsSheepBiocompatible MaterialsHydroxyapatiteshydroxyapatite-tricalciumphosphate compositeNacre

Identifiers

PMID32149098
PMCPMC7049417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.