Evidence map›Paper›PMID 32149081›Full record

ArticleBioMed research international2020

Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma.

Hexiang Wang, Zhenyou Liu, Yong Zhang, Feng Hou, Weiwei Fu, Jizheng Lin, Yingchao Liu, Xuejun Liu

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Fn14-Targeted Gold Nanorods for Augmenting Laser Thermal Therapy for High-Grade Gliomas.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  3. Article
  4. Observational
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hexiang WangDepartment of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0003-1027-055X
Zhenyou LiuDepartment of Radiology, Qingdao Eighth People's Hospital, Qingdao, Shandong, China.
Yong ZhangDepartment of Radiology, The Xixiu District People's Hospital, Anshun, Guizhou, China.
Feng HouDepartment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Weiwei FuDepartment of Pathology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Jizheng LinDepartment of Radiology, Qingdao Eighth People's Hospital, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0001-7296-7921
Yingchao LiuDepartment of Neurosurgery, Shandong Provincial Hospital Jinan, Jinan, Shandong, China.
Xuejun LiuDepartment of Radiology, Qingdao Eighth People's Hospital, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0002-3250-4778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was performed to determine whether diffusion-weighted imaging (DWI) plus unenhanced computed tomography (CT) of the brain increases the diagnostic value of routine magnetic resonance (MR) imaging findings of early-stage glioblastoma.

methodsPostcontrast MR images of eight unenhanced lesions that had been pathologically diagnosed as glioblastoma were retrospectively examined. The location, margin, signal intensity, and attenuation on MR imaging and CT were assessed.

resultsOn MR imaging, all lesions were ill-defined, small, and isointense to hypointense on T1-weighted images and hyperintense on T2-weighted images. Four patients had perilesional edema. In seven patients, DWI showed an inhomogeneous hyperintense lesion (

conclusionsMR imaging was the most sensitive imaging method for depicting early-stage glioblastoma. The CT finding of a hyperattenuated or isoattenuated region combined with the DWI finding of the same region containing an inhomogeneous hyperintense lesion or isointense lesion with a hyperintense region may be a specific diagnostic sign for early-stage glioblastoma. DWI plus unenhanced CT added diagnostic value to the routine MR imaging findings of early-stage glioblastoma.

Indexed as

AdultAgedBrainDiffusion Magnetic Resonance ImagingFemaleGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID32149081
PMCPMC7049329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.