Evidence map›Paper›PMID 32149077›Full record

ArticleBioMed research international2020

Nomogram for Individualized Prediction of Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis on Conservative Treatment.

Yao Liu, Dongying Xue, Xiaogang Zhang, Fangyuan Gao, Le Sun, Xue Yang, Yuxin Li, Qun Zhang, Bingbing Zhu, Shuaishuai Niu and 3 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Yao LiuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Dongying XueDepartment of Infections Disease, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Xiaogang ZhangInstitute of Liver Diseases, Third People's Hospital of Changzhou, Changzhou 213000, China.
Fangyuan GaoCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Le SunCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Xue YangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Yuxin LiCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.ORCID https://orcid.org/0000-0002-1854-3391
Qun ZhangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Bingbing ZhuDepartment of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Shuaishuai NiuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Yunyi HuangDepartment of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Ying HuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Xianbo WangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.ORCID https://orcid.org/0000-0003-1671-1934
Capital Medical University · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNChangzhou Third People's Hospital · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal vein tumor thrombosis (PVTT) is one of the major predictive factors for patients with hepatocellular carcinoma (HCC). The objective of this study was to establish a prognostic nomogram for identifying individual survival outcomes in patients with HCC and PVTT on conservative treatment based on specific factors.

methodsTwo hundred and ten patients with HCC and PVTT on conservative treatment in Beijing Ditan Hospital between June 2008 and May 2017 were studied retrospectively as a derivation cohort. We built a nomogram based on independent risk factors for survival prediction. The concordance index (c-index) and a calibration curve were used to evaluate the predictive accuracy. During the study, 102 patients were included at the Putuo Hospital and Third People's Hospital of Changzhou as a validation cohort.

resultsIn the derivation cohort, the independent factors for overall survival were identified by multivariate analysis, namely, aspartate aminotransferase ≥119 IU/L, gamma-glutamyl transferase ≥115 IU/L, Child-Pugh class C liver function, creatinine ≥91

conclusionsThe nomogram can be a more accurate and individualized prediction for 6-month overall survival of patients with HCC and PVTT on conservative treatment, and it is possible to consider further active interventions for patients in the low-risk group (0-85 scores) to achieve the aim of prolonging survival.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsVenous ThrombosisAdultAgedAged, 80 and overConservative TreatmentFemaleHumansMaleMiddle AgedNomogramsPortal VeinRetrospective StudiesSurvival Analysis

Identifiers

PMID32149077
PMCPMC7049328
OpenAlexW3006257973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.