Evidence map›Paper›PMID 32149076›Full record

ArticleBioMed research international2020

DMBA-Induced Oral Carcinoma in Syrian Hamster: Increased Carcinogenic Effect by Dexamethasone Coexposition.

Diana A Martínez B, Paola Andrea Barato Gómez, Carlos Arturo Iregui Castro, Jaiver E Rosas Pérez

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Diana A Martínez BDepartment of Pharmacy, Sciences Faculty, Universidad Nacional de Colombia, Bogotá 111321, Colombia.ORCID https://orcid.org/0000-0003-3051-1808
Paola Andrea Barato GómezCorporación Patología Veterinaria (CORPAVET), Bogotá 111321, Colombia.
Carlos Arturo Iregui CastroGroup of Veterinary Pathobiology, Universidad Nacional de Colombia, Bogotá 111321, Colombia.ORCID https://orcid.org/0000-0003-0790-8305
Jaiver E Rosas PérezDepartment of Pharmacy, Sciences Faculty, Universidad Nacional de Colombia, Bogotá 111321, Colombia.ORCID https://orcid.org/0000-0001-5229-2007
Universidad Nacional de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of systemic administration of the immunosuppressant dexamethasone (DM) while inducing hamster buccal pouch DMBA carcinogenesis.

resultsThe time of macroscopic neoplasm development was reduced when DM-DMBA coexposition was employed, finding tumors after 10-12 weeks of exposition. In addition, the frequency of histopathological lesions was higher.

conclusionImmunomodulatory action of dexamethasone may reduce the time of oral squamous cell carcinoma (OSCC) induction and may increase the incidence of neoplasms developed.

Indexed as

9,10-Dimethyl-1,2-benzanthraceneAnimalsCarcinogensCarcinoma, Squamous CellCricetinaeDexamethasoneMaleMesocricetusMouth MucosaMouth Neoplasms9,10-Dimethyl-1,2-benzanthraceneCarcinogensDexamethasone

Identifiers

PMID32149076
PMCPMC7042540
OpenAlexW3006465373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.