ArticleWorld journal of clinical cases2020
Thyroid metastasis from breast cancer presenting with enlarged lateral cervical lymph nodes: A case report.
Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Article
- Double trouble: Tumor-to-tumor metastasis of breast cancer into a thyroid papillary carcinoma - Case report and review of literature.International journal of surgery case reports · 2025Article
- Case Report: A rare case of thyroid metastasis from breast cancer.Frontiers in oncology · 2025Article
- Thyroid Metastases from Breast Cancer Case Report and Literature Review.Current cancer drug targets · 2025Review
- Thyroid Metastasis from Primary Breast Cancer.Journal of clinical medicine · 2023Review
- Occult breast cancer metastasis to the thyroid gland: Case report.Clinical case reports · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSecondary malignancy of the thyroid occurs infrequently and mainly originates from malignant tumors of the kidney, gastrointestinal tract, lungs, breast, and skin. The correct diagnosis is important but difficult. Importantly, there are major differences in the treatment of primary and metastatic thyroid cancer, which has a significant impact on prognosis and survival. Therefore, how to diagnose thyroid metastasis (TM) correctly before surgery is a major concern for surgeons. CASE SUMMARY: We report a 38-year-old woman who presented with palpable cervical lymph nodes after breast cancer (BC) surgery 2 years ago. Ultrasonography and computed tomography revealed thyroid nodules with irregular margins and enlarged cervical lymph nodes. Biopsy was performed for the right largest cervical lymph node, and immunohistochemical analysis revealed negativity for thyroglobulin, estrogen receptor, and progestin receptor and positive for human epidermal growth factor receptor 2. The diagnosis was TM from BC with cervical lymph node metastasis. Total thyroidectomy with bilateral central and lateral neck lymph node dissection was performed. After a 5-mo follow-up, no recurrence or novel distant metastasis was identified.
conclusionTM from BC is a rare secondary malignancy. Broad differential diagnosis by biopsy and immunohistochemical analysis needs to be considered.
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