ArticleWorld journal of clinical cases2020
Risk factors for postoperative sepsis in patients with gastrointestinal perforation.
Article in World journal of clinical cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Effects of Shenling Chengqi Decoction on Gastrointestinal Function and Immune Status of Patients with Gastrointestinal Injury in Severe Sepsis.Computational and mathematical methods in medicine · 2022Trial
- Prognostic determinants in surgical critial patients undergoing emergency surgery for Stage III or higher colorectal cancer.Langenbeck's archives of surgery · 2025Article
- Prognostic factors in patients with gastrointestinal perforation under the acute care surgery model : a retrospective cohort study.BMC surgery · 2024Article
- Risk factors for sepsis in patients with colorectal cancer complicated with gastrointestinal perforation and its impact on prognosis.Journal of gastrointestinal oncology · 2023Article
- Nomogram for predicting the prognosis of tumor patients with sepsis after gastrointestinal surgery.World journal of gastrointestinal oncology · 2022Article
- Bacterial translocation in patients undergoing major gastrointestinal surgery and its role in postoperative sepsis.World journal of gastrointestinal pathophysiology · 2021Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis is fatal in patients with gastrointestinal perforation (GIP). However, few studies have focused on this issue.
aimTo investigate the risk factors for postoperative sepsis in patients with GIP.
methodsThis was a retrospective study performed at the Department of General Surgery in our treatment center. From January 2016 to December 2018, the medical records of patients with GIP who underwent emergency surgery were reviewed. Patients younger than 17 years or who did not undergo surgical treatment were excluded. The patients were divided into the postoperative sepsis group and the non-postoperative sepsis group. Clinical data for both groups were collected and compared, and the risk factors for postoperative sepsis were investigated. The institutional ethical committee of our hospital approved the study.
resultsTwo hundred twenty-six patients were admitted to our department with GIP. Fourteen patients were excluded: Four were under 17 years old, and 10 did not undergo emergency surgery due to high surgical risk and/or disagreement with the patients and their family members. Two hundred twelve patients were finally enrolled in the study; 161 were men, and 51 were women. The average age was 62.98 ± 15.65 years. Postoperative sepsis occurred in 48 cases. The prevalence of postoperative sepsis was 22.6% [95% confidence interval (CI): 17.0%-28.3%]. Twenty-eight patients (13.21%) died after emergency surgery. Multiple logistic regression analysis confirmed that the time interval from abdominal pain to emergency surgery [odds ratio (OR) = 1.021, 95%CI: 1.005-1.038,
conclusionThe time interval from abdominal pain to surgery, colonic perforation, diameter of perforation, and the incidence of malignant tumor-related perforation were risk factors for postoperative sepsis in patients with GIP.
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