Evidence map›Paper›PMID 32149044›Full record

ArticleMedical mycology case reports2020

The robust and rapid role of molecular testing in precision fungal diagnostics: A case report.

Julie M Steinbrink, David K Hong, Stephen P Bergin, Rami N Al-Rohil, John R Perfect, Eileen K Maziarz

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medical mycology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Roles of theJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Mucormycosis.Infectious disease clinics of North America · 2021
    Review
  6. Budget Impact of Microbial Cell-Free DNA Testing Using the KariusApplied health economics and health policy · 2021
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Julie M SteinbrinkDivision of Infectious Diseases, Duke University Medical Center, Durham, NC, USA.
David K HongKarius, Inc, Redwood City, USA.
Stephen P BerginDivision of Pulmonary, Allergy, and Critical Care, Duke University Medical Center, Durham, NC, USA.
Rami N Al-RohilDepartment of Pathology, Duke University Medical Center, Durham, NC, USA.
John R PerfectDivision of Infectious Diseases, Duke University Medical Center, Durham, NC, USA.
Eileen K MaziarzDivision of Infectious Diseases, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · US

Funding

Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDSR01AI093257 · NIAID · DUKE UNIVERSITY · PI PERFECT, JOHN R. · 2011 to 2022
$3.8M
Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTGT32AI100851 · NIAID · DUKE UNIVERSITY · PI ALEXANDER, BARBARA D · 2013 to 2022
$1.8M
NIAID NIH HHS R01 AI093257NIAID NIH HHS T32 AI100851
6 · The paper itself

Abstract

Diagnosis of invasive fungal disease remains an ongoing challenge for clinicians, while continuously evolving treatment regimens increase patient risk for invasive infection. This case highlights how molecular testing led to the diagnosis of co-infection with two fungal pathogens producing invasive disease in a hematopoietic stem cell transplant recipient with graft-versus-host disease (GVHD).

Indexed as

AspergillusCunninghamellaIbrutinibInvasive fungal infectionMolecular diagnostics

Identifiers

PMID32149044
PMCPMC7033287
OpenAlexW3006180373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.