Evidence map›Paper›PMID 32148986›Full record

ArticleCase reports in ophthalmological medicine2020

Commercial Cannabinoid Oil-Induced Stevens-Johnson Syndrome.

Han Y Yin, Nicholas Hadjokas, Kanish Mirchia, Robert Swan, Samuel Alpert

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Han Y YinDepartment of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID https://orcid.org/0000-0002-1808-3532
Nicholas HadjokasDepartment of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.
Kanish MirchiaDepartment of Pathology, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID https://orcid.org/0000-0002-7371-7059
Robert SwanDepartment of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.ORCID https://orcid.org/0000-0003-3923-5811
Samuel AlpertDepartment of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.
SUNY Upstate Medical University · USFlorida International University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report an unusual presentation of commercial cannabidiol (CBD) oil-induced Stevens-Johnson Syndrome/toxic epidermal necrolysis (SJS-TEN).

methodsA 56-year-old woman presented with acute onset of a diffuse, blistering, maculopapular rash with over 30% total body surface area (BSA) involvement two days after taking CBD oil sublingually for chronic pain. Biopsy confirmed SJS-TEN. Ophthalmology was consulted and mild eye involvement was found. She was started on topical cyclosporine, prednisone, moxifloxacin, and erythromycin ointment to prevent progression, which was successful. She was otherwise treated with supportive therapy in the intensive care burn unit and ultimately passed away from septic shock.

conclusionIn this case, we described an unusual drug-induced SJS from a commercial, non-FDA-regulated cannabis product. The use of a commercial CBD product should be cautioned due to potential for series of drug reactions to the cannabis product and the risk for reaction to other unregulated other pharmacological components.

Identifiers

PMID32148986
PMCPMC7053463
OpenAlexW3008546667

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.