Evidence map›Paper›PMID 32148775›Full record

ReviewF1000Research2020

Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans.

Sophie Joanisse, Changhyun Lim, James McKendry, Jonathan C Mcleod, Tanner Stokes, Stuart M Phillips

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

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  16. Is the myonuclear domain ceiling hypothesis dead?Singapore medical journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sophie JoanisseExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
Changhyun LimExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
James McKendryExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
Jonathan C McleodExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
Tanner StokesExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.
Stuart M PhillipsExercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-1956-4098
McMaster University · CA

Funding

CIHR
6 · The paper itself

Abstract

Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity of skeletal muscle are relevant, and resistance exercise is foundational to the process of functional hypertrophy. Much of our current understanding of skeletal muscle hypertrophy can be attributed to the development and utilization of stable isotopically labeled tracers. We know that resistance exercise and sufficient protein intake act synergistically and provide the most effective stimuli to enhance skeletal muscle mass; however, the molecular intricacies that underpin the tremendous response variability to resistance exercise-induced hypertrophy are complex. The purpose of this review is to discuss recent studies with the aim of shedding light on key regulatory mechanisms that dictate hypertrophic gains in skeletal muscle mass. We also aim to provide a brief up-to-date summary of the recent advances in our understanding of skeletal muscle hypertrophy in response to resistance training in humans.

Indexed as

Resistance TrainingHumansMuscle, Skeletalhypertrophymuscleproteinresistance exercise

Identifiers

PMID32148775
PMCPMC7043134
OpenAlexW3008363345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.