Evidence map›Paper›PMID 32148766›Full record

ReviewF1000Research2020

Pulsed actomyosin contractions in morphogenesis.

Ann Sutherland, Alyssa Lesko

Abstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. A thermodynamic perspective on mammalian neural crest ingression.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ann SutherlandDepartment of Cell Biology, University of Virginia Health System, Charlottesville, VA, USA.ORCID 0000-0003-1925-2825
Alyssa LeskoDepartment of Cell Biology, University of Virginia Health System, Charlottesville, VA, USA.

Funding

Vangl2 function in mammalian convergent extensionR01HD087093 · NICHD · UNIVERSITY OF VIRGINIA · PI SUTHERLAND, ANN E · 2016 to 2020
$1.6M
Zeiss 780 NLO High Sensitivity Multiphoton Microscopy SystemS10OD016446 · OD · UNIVERSITY OF VIRGINIA · PI PERIASAMY, AMMASI · 2013 to 2013
$600k
Tunable White Light Laser Confocal/Spectral Imaging MicroscopyS10RR025616 · NCRR · UNIVERSITY OF VIRGINIA · PI PERIASAMY, AMMASI · 2009 to 2009
$500k
NCRR NIH HHS S10 RR025616NICHD NIH HHS R01 HD087093NIH HHS S10 OD016446
6 · The paper itself

Abstract

Cell and tissue shape changes are the fundamental elements of morphogenesis that drive normal development of embryos into fully functional organisms. This requires a variety of cellular processes including establishment and maintenance of polarity, tissue growth and apoptosis, and cell differentiation, rearrangement, and migration. It is widely appreciated that the cytoskeletal networks play an important role in regulating many of these processes and, in particular, that pulsed actomyosin contractions are a core cellular mechanism driving cell shape changes and cell rearrangement. In this review, we discuss the role of pulsed actomyosin contractions during developmental morphogenesis, advances in our understanding of the mechanisms regulating actomyosin pulsing, and novel techniques to probe the role of pulsed actomyosin processes in

Indexed as

Cell PolarityActomyosinCell ShapeCytoskeletonMorphogenesisActomyosinactomyosinapical constrictionmorphogenesispulsed contractions

Identifiers

PMID32148766
PMCPMC7043108

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.