Evidence map›Paper›PMID 32148439›Full record

ArticleMediators of inflammation2020

Analysis of Myocardial Ischemia Parameters after Coronary Artery Bypass Grafting with Minimal Extracorporeal Circulation and a Novel Microplegia versus Off-Pump Coronary Artery Bypass Grafting.

Luca Koechlin, Urs Zenklusen, Thomas Doebele, Bejtush Rrahmani, Brigitta Gahl, Thibault Schaeffer, Denis Berdajs, Friedrich S Eckstein, Oliver Reuthebuch

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. The Effects of Obesity on Mortality Following Coronary Artery Bypass Graft Surgery: A Retrospective Study from a Single Center in China.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Luca KoechlinDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0002-2929-8600
Urs ZenklusenDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Thomas DoebeleDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Bejtush RrahmaniDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Brigitta GahlDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Thibault SchaefferDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Denis BerdajsDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Friedrich S EcksteinDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Oliver ReuthebuchDepartment of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.ORCID https://orcid.org/0000-0003-1386-0686
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the performance of our institutionally refined microplegia protocol in conjunction with minimal extracorporeal circulation system (MiECC) with off-pump coronary artery bypass grafting (OPCAB).

methodsWe conducted a single center study including patients undergoing isolated CABG surgery performed either off-pump or on-pump using our refined microplegia protocol in conjunction with MiECC. We used propensity modelling to calculate the inverse probability of treatment weights (IPTW). Primary endpoints were peak values of high

resultsAfter IPTW, we could include 278 patients into our analyses, 153 of which had received OPCAB and 125 of which had received microplegia. Standardized differences indicated that treatment groups were comparable after IPTW. The multivariable quantile regression yielded a nonsignificant median increase of first hs-cTnT by 39 ng/L (95% CI -8 to 87 ng/L,

conclusionThe use of our institutionally refined microplegia in conjunction with MiECC was associated with similar results with regard to ischemic injury, expressed in hs-cTnT compared to OPCAB. MACCE was seen equally frequent. ICU discharge was earlier if microplegia was used.

Indexed as

AgedCoronary Artery BypassCoronary Artery Bypass, Off-PumpCoronary Artery DiseaseCreatine Kinase, MB FormExtracorporeal CirculationFemaleHumansMaleMiddle AgedMyocardial IschemiaRisk FactorsTroponin TCreatine Kinase, MB FormTroponin T

Identifiers

PMID32148439
PMCPMC7056992
OpenAlexW3002945773

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.