Evidence map›Paper›PMID 32148437›Full record

ArticleMediators of inflammation2020

Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy.

Wenhua Xu, Mingshan Ren, Swagata Ghosh, Kai Qian, Zhaofeng Luo, Aimei Zhang, Cuiping Zhang, Jiajun Cui

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Regulatory T Cells-Related Genes Are under DNA Methylation Influence.International journal of molecular sciences · 2021
    Review
  7. Deciphering DNA Methylation in HIV Infection.Frontiers in immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Wenhua XuDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0002-6990-2542
Mingshan RenDepartment of Neurology, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Swagata GhoshDepartment of Internal Medicine, Division of Infectious Diseases and International Health, University of Virginia, Virginia 22908, USA.
Kai QianThe Center for Translational Medicine, Yichun University, Yichun, China.
Zhaofeng LuoHefei National Laboratory for Physical Science, Core Facility Center for Life Sciences, University of Science and Technology of China, Hefei, China.
Aimei ZhangCentral Laboratory, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Cuiping ZhangCentral Laboratory, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China.
Jiajun CuiThe Center for Translational Medicine, Yichun University, Yichun, China.ORCID https://orcid.org/0000-0002-9000-371X
University of Science and Technology of China · CNYichun University · CNUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is a CD4

Indexed as

AdultCD4-Positive T-LymphocytesCTLA-4 AntigenDendritic CellsEnzyme-Linked Immunosorbent AssayFemaleFlow CytometryHumansImmunoglobulins, IntravenousLipopolysaccharide ReceptorsMaleMiddle AgedMyasthenia GravisReal-Time Polymerase Chain ReactionT-LymphocytesT-Lymphocytes, RegulatoryCTLA-4 AntigenImmunoglobulins, IntravenousLipopolysaccharide Receptors

Identifiers

PMID32148437
PMCPMC7042523
OpenAlexW3006665844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.