Evidence map›Paper›PMID 32148380›Full record

ArticleWorld journal of gastroenterology2020

Haemoglobin, albumin, lymphocyte and platelet predicts postoperative survival in pancreatic cancer.

Shuai-Shuai Xu, Shuo Li, Hua-Xiang Xu, Hao Li, Chun-Tao Wu, Wen-Quan Wang, He-Li Gao, Wang Jiang, Wu-Hu Zhang, Tian-Jiao Li and 3 more

Registry-linked trialOpen access · bronzeAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05506748 (Association Between Preoperative HALP and Immediate Postoperative Outcomes in Patients Undergoing Pancreaticoduodenectomy), which is not on this map. Cited by 97 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05506748 completednot on this mapstarted 2021, after this paper: background citation

Association Between Preoperative HALP and Immediate Postoperative Outcomes in Patients Undergoing Pancreaticoduodenectomy

TypeobservationalSponsorChitwan Medical CollegeRan2021 to 2022Enrolled22ConditionsHemoglobins, Albumins, Platelets, LymphocytesArmspantients undergoing pancreaticoduodenectomy
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 4 syntheses or guidelines pooled it, 158 citations in OpenAlex.

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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Shuai-Shuai XuDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Shuo LiDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Hua-Xiang XuDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Hao LiDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Chun-Tao WuDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Wen-Quan WangDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
He-Li GaoDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Wang JiangDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Wu-Hu ZhangDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Tian-Jiao LiDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Quan-Xing NiDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Liang LiuDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Xian-Jun YuDepartment of Pancreatic Surgery, Fudan University, Shanghai Cancer Center, Shanghai 20032, China.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic inflammation and nutrition status play an important role in cancer metastasis. The combined index of hemoglobin, albumin, lymphocyte, and platelet (HALP), consisting of haemoglobin, albumin, lymphocytes, and platelets, is considered as a novel marker to reflect both systemic inflammation and nutrition status. However, no studies have investigated the relationship between HALP and survival of patients with pancreatic cancer following radical resection.

aimTo evaluate the prognostic value of preoperative HALP in pancreatic cancer patients.

methodsThe preoperative serum levels of hemoglobin, albumin, lymphocyte counts, and platelet counts were routinely detected in 582 pancreatic adenocarcinoma patients who underwent radical resection. The relationship between postoperative survival and the preoperative level of HALP was investigated.

resultsLow levels of HALP were significantly associated with lymph node metastasis (

conclusionLow levels of HALP may be a significant risk factor for RFS and OS in patients with resected pancreatic cancer.

Indexed as

Blood PlateletsAdenocarcinomaAdultAgedAged, 80 and overFemaleHemoglobinsHumansMaleMiddle AgedNutritional StatusPancreatectomyPancreatic NeoplasmsPlatelet CountPredictive Value of TestsPreoperative PeriodHemoglobinsSerum AlbuminHALPNutrition statusPancreatic adenocarcinomaPostoperative survivalSystemic inflammation

Identifiers

PMID32148380
PMCPMC7052532
OpenAlexW3007816896

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.