Evidence map›Paper›PMID 32148197›Full record

ArticleCurrent neuropharmacology2021

Sleep Disturbances and Cognitive Impairment in the Course of Type 2 Diabetes-A Possible Link.

Anna Brzecka, Natalia Madetko, Vladimir N Nikolenko, Ghulam M Ashraf, Maria Ejma, Jerzy Leszek, Cyryl Daroszewski, Karolina Sarul, Liudmila M Mikhaleva, Siva G Somasundaram and 3 more

Open access · greenAbstract read
In one paragraph

Article in Current neuropharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Anna BrzeckaDepartment of Pulmonology and Lung Cancer, Wroclaw Medical University, Wroclaw, Poland.
Natalia MadetkoDepartment of Neurology, Wroclaw Medical University, Wroclaw, Poland.
Vladimir N NikolenkoI. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russian Federation.
Ghulam M AshrafKing Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Maria EjmaDepartment of Neurology, Wroclaw Medical University, Wroclaw, Poland.
Jerzy LeszekDepartment of Psychiatry, Wroclaw Medical University, Wroclaw, Poland.
Cyryl DaroszewskiDepartment of Pulmonology and Lung Cancer, Wroclaw Medical University, Wroclaw, Poland.
Karolina SarulDepartment of Pulmonology and Lung Cancer, Wroclaw Medical University, Wroclaw, Poland.
Liudmila M MikhalevaResearch Institute of Human Morphology,3 Tsyurupy Street, Moscow, 117418, Russian Federation.
Siva G SomasundaramDepartment of Biological Sciences, Salem University, Salem, WV, 26426, United States.
Cecil E KirklandDepartment of Biological Sciences, Salem University, Salem, WV, 26426, United States.
Sergey O BachurinInstitute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, 142432, Russian Federation.
Gjumrakch AlievI. M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 8/2 Trubetskaya Str., Moscow, 119991, Russian Federation.
Wroclaw Medical University · PLSalem University · USSechenov University · RUInstitute of Physiologically Active Compounds · RUKing Abdulaziz University · SAResearch Institute of Human Morphology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an increasing number of patients worldwide with sleep disturbances and diabetes. Various sleep disorders, including long or short sleep duration and poor sleep quality of numerous causes, may increase the risk of diabetes. Some symptoms of diabetes, such as painful peripheral neuropathy and nocturia, or associated other sleep disorders, such as sleep breathing disorders or sleep movement disorders, may influence sleep quality and quantity. Both sleep disorders and diabetes may lead to cognitive impairment. The risk of development of cognitive impairment in diabetic patients may be related to vascular and non-vascular and other factors, such as hypoglycemia, hyperglycemia, central insulin resistance, amyloid and tau deposits and other causes. Numerous sleep disorders, e.g., sleep apnea, restless legs syndrome, insomnia, and poor sleep quality are most likely are also associated with cognitive impairment. Adequate functioning of the system of clearance of the brain from toxic substances, such as amyloid β, i.e. glymphatic system, is related to undisturbed sleep and prevents cognitive impairment. In the case of coexistence, sleep disturbances and diabetes either independently lead to and/or mutually aggravate cognitive impairment.

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2Sleep Wake DisordersAmyloid beta-PeptidesHumansSleepAmyloid beta-Peptidescentral nervous systemdementiaglymphatic systemhyperglycemiahypoglycemiaInsulinrisk factorssleep apnea

Identifiers

PMID32148197
PMCPMC7903492
OpenAlexW3011961578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.