Evidence map›Paper›PMID 32148161›Full record

ArticleLeukemia & lymphoma2020

Cognitive function in patients with chronic lymphocytic leukemia: a cross-sectional study examining effects of disease and treatment.

AnnaLynn M Williams, Edwin van Wijngaarden, Christopher L Seplaki, Charles E Heckler, Miriam T Weber, Paul M Barr, Clive S Zent, Michelle C Janelsins

Open access · greenAbstract read
In one paragraph

Article in Leukemia & lymphoma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Fitness in CLL.Cancers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Short-Term Impact of Hematopoietic Stem Cell Transplantation on Depressive Behavior, Cognition and Quality of Life in Leukemia Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

AnnaLynn M WilliamsDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
Edwin van WijngaardenDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
Christopher L SeplakiDepartment of Public Health Sciences, University of Rochester Medical Center, Rochester, NY, USA.
Charles E HecklerDepartment of Surgery, University of Rochester Medical Center, Rochester, NY, USA.
Miriam T WeberDepartment of Neurology, University of Rochester Medical Center, Rochester, NY, USA.
Paul M BarrJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Clive S ZentJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
Michelle C JanelsinsJames P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA.
University of Rochester Medical Center · US

Funding

URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Clinical and Translational Cancer Control Research Training ProgramT32CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, Gary R Morrow · 2019 to 2026
$2.7M
Clinical and Translational Approaches to Cognitive Impairments in CancerDP2CA195765 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C · 2014 to 2014
$2.3M
Interventions Targeting Inflammation for Chemotherapy-Related Cognitive ProblemsK07CA168886 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C · 2013 to 2017
$724k
Understanding neuropsychological and psychosocial sequelae in the elderly and in adolescent and young adult cancer survivorsK00CA222742 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WILLIAMS, ANNALYNN · 2019 to 2020
$180k
Understanding neuropsychological and psychosocial sequelae in the elderly and in adolescent and young adult cancer survivorsF99CA222742 · NCI · UNIVERSITY OF ROCHESTER · PI WILLIAMS, ANNALYNN · 2017 to 2018
$67k
NCI NIH HHS DP2 CA195765NCI NIH HHS F99 CA222742NCI NIH HHS K00 CA222742NCI NIH HHS K07 CA168886NCI NIH HHS T32 CA102618NCI NIH HHS UG1 CA189961
6 · The paper itself

Abstract

Cancer-related cognitive impairment (CRCI) has not been objectively assessed in chronic lymphocytic leukemia (CLL). It is currently unclear how much of CRCI is attributable to disease, treatment, or both. We used CLL as a novel model to study the differential roles of disease and treatment in CRCI. One hundred and fifty CLL patients (100 treatment-naïve and 50 chemotherapy-treated) including 84 patients with higher-risk of CLL progression completed objective neuropsychological tests. Sociodemographic-adjusted linear regression models examined cognitive outcomes in relation to risk and treatment. Higher-risk patients recalled two fewer words on a memory task (

Indexed as

Cognitive DysfunctionLeukemia, Lymphocytic, Chronic, B-CellLeukemia, Myeloid, AcuteCognitionCross-Sectional StudiesHumanschemotherapyChronic lymphocytic leukemiacognitive impairmenttreatment naïve

Identifiers

PMID32148161
PMCPMC7384931
OpenAlexW3009925303

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.