ArticleHypertension (Dallas, Tex. : 1979)2020
Hypothalamic Paraventricular Nucleus Gαi
Open access · bronzeAbstract read
In one paragraph
Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Multi-Omics Mendelian Randomization Maps Lipid-Related Brain Cell-Type Associations with Kidney Disease.Genes · 2026Article
- Central nervous system mechanisms of salt-sensitive hypertension.Physiological reviews · 2025Review
- Silent Effects of High Salt: Risks Beyond Hypertension and Body's Adaptation to High Salt.Biomedicines · 2025Review
- Integrated renal and sympathetic mechanisms underlying the development of sex- and age-dependent hypertension and the salt sensitivity of blood pressure.GeroScience · 2024Article
- Sex differences in dietary sodium evoked NCC regulation and blood pressure in male and female Sprague-Dawley, Dahl salt-resistant, and Dahl salt-sensitive rats.American journal of physiology. Renal physiology · 2024Article
- Renal denervation restores biomechanics of carotid arteries in a rat model of hypertension.Scientific reports · 2024Article
- Central GαiFrontiers in endocrinology · 2022Review
- The Emerging Scenario of the Gut-Brain Axis: The Therapeutic Actions of the New Actor Kefir against Neurodegenerative Diseases.Antioxidants (Basel, Switzerland) · 2021Review
- Fibronectin type III domain-containing 5 in cardiovascular and metabolic diseases: a promising biomarker and therapeutic target.Acta pharmacologica Sinica · 2021Article
- Salt sensitivity and hypertension.Journal of human hypertension · 2021Review
- Sensory Afferent Renal Nerve Activated GαiFrontiers in physiology · 2021Article
- Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent αFrontiers in physiology · 2021Article
- Neuroanatomical characterization of GαiPhysiological genomics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Casey Y CarmichaelFrom the Department of Pharmacology and Experimental Therapeutics and The Whitaker Cardiovascular Institute (C.Y.C., J.T.K., J.D.M., S.E.M., R.D.W.), Boston University School of Medicine, MA.
Jill T KuwabaraFrom the Department of Pharmacology and Experimental Therapeutics and The Whitaker Cardiovascular Institute (C.Y.C., J.T.K., J.D.M., S.E.M., R.D.W.), Boston University School of Medicine, MA.
Crissey L PascaleDepartment of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA (C.L.P., D.R.K.).
Jesse D MoreiraFrom the Department of Pharmacology and Experimental Therapeutics and The Whitaker Cardiovascular Institute (C.Y.C., J.T.K., J.D.M., S.E.M., R.D.W.), Boston University School of Medicine, MA.
Sarah E MahneFrom the Department of Pharmacology and Experimental Therapeutics and The Whitaker Cardiovascular Institute (C.Y.C., J.T.K., J.D.M., S.E.M., R.D.W.), Boston University School of Medicine, MA.
Daniel R KapustaDepartment of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA (C.L.P., D.R.K.).
Douglas L RoseneDepartment of Anatomy & Neurobiology (D.L.R.), Boston University School of Medicine, MA.
Jonathan S WilliamsDivision of Endocrinology, Diabetes, Hypertension, Brigham and Women's, Harvard Medical School, Boston, MA (J.S.W.).
J Thomas CunninghamDepartment of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX (J.T.C.).
Richard D WainfordFrom the Department of Pharmacology and Experimental Therapeutics and The Whitaker Cardiovascular Institute (C.Y.C., J.T.K., J.D.M., S.E.M., R.D.W.), Boston University School of Medicine, MA.
Cardiovascular Institute of the South · USBoston University · USLouisiana State University Health Sciences Center New Orleans · USHarvard University · US
Funding
Multidisciplinary Training in Cardiovascular ResearchT32HL007224 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAMBURG, NAOMI MIRIAM, WAINFORD, RICHARD DAVID · 1985 to 2020
$12.3MVascular and Cardiac Function Core - "Mentoring in Cardiovascular BiologyP30GM106392 · NIGMS · LSU HEALTH SCIENCES CENTER · PI FILIPEANU, CATALIN · 2014 to 2018
$5.5MAging and hypertension: Integrated renal and sympathetic control of blood pressureR01AG062515 · NIA · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2019 to 2023
$3.5MCentral mechanisms and novel biomarkers of the salt-sensitivity of blood pressureR01HL141406 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.8MNeural control of the kidney and long-term blood pressure regulationR01HL139867 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.6MNeural Regulation of Vasopressin Release in a Model of Dilutional HyponatremiaR01HL142341 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI CUNNINGHAM, J THOMAS · 2018 to 2021
$2.2MBrain G-alpha subunit protein mediated neural control of blood pressureR01HL107330 · NHLBI · LSU HEALTH SCIENCES CENTER · PI WAINFORD, RICHARD DAVID · 2011 to 2015
$1.9MAging and hypertension: Integrated renal and sympathetic control of blood pressureR56AG057687 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WAINFORD, RICHARD DAVID · 2018 to 2018
$731kBrain G-alpha subunit protein mediated neural control of blood pressureK02HL112718 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WAINFORD, RICHARD DAVID · 2013 to 2017
$577kRenal and Neural Mechanisms of Age-Related HypertensionF31DK116501 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FRAME, ALISSA A · 2017 to 2018
$92kNHLBI NIH HHS K02 HL112718NHLBI NIH HHS R01 HL107330NHLBI NIH HHS R01 HL139867NHLBI NIH HHS R01 HL141406NHLBI NIH HHS R01 HL142341NHLBI NIH HHS T32 HL007224NIA NIH HHS R01 AG062515NIA NIH HHS R56 AG057687NIDDK NIH HHS F31 DK116501NIGMS NIH HHS P30 GM106392
Abstract
We have previously reported that in salt-resistant rat phenotypes brain, Gαi
Indexed as
Sodium Chloride, DietaryAnimalsBlood PressureGTP-Binding Protein alpha Subunit, Gi2HypertensionKidneyMaleNatriuresisNeural PathwaysParaventricular Hypothalamic NucleusRatsRats, Sprague-DawleySignal TransductionGTP-Binding Protein alpha Subunit, Gi2Sodium Chloride, DietaryG alpha i 2 proteinshypertensionnorepinephrineparaventricular nucleusrenal sympathetic nerves
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.