Evidence map›Paper›PMID 32147884›Full record

ArticleJournal of clinical laboratory analysis2020

Comparison of electrolyte and glucose levels measured by a blood gas analyzer and an automated biochemistry analyzer among hospitalized patients.

Huo-Chun Yi, Wen-Sheng Shi, Yin-Hui Zhang, Xiao-Zhen Zhu, Yang Yu, Xin-Xin Wang, Zhang Dai, Yong Lin

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of clinical laboratory analysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparison of Sodium, Potassium, Hemoglobin, and Glucose Levels by Blood Gas Analyzer and Hospital Laboratory Autoanalyzer in Emergency Department Settings: A Cross-sectional Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  4. ABG Analyzer for Electrolyte Measurement in ICU Patients: To Do or Not to Do.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  5. A Retrospective Database Analysis to Investigate if Electrolytes in Venous Blood are Equivalent to the Levels in Arterial Blood.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
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  7. Article
  8. Article
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  10. Article
  11. Blood Glucose Monitoring in the Neonatal Period: A Study on Evaluation Using the RAPIDPoint 500/500e.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Huo-Chun YiCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Wen-Sheng ShiCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Yin-Hui ZhangDepartment of Medical Laboratory, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, China.
Xiao-Zhen ZhuCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Yang YuCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Xin-Xin WangCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Zhang DaiCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.
Yong LinCenter of Clinical Laboratory, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0001-5120-8221
Zhongshan Hospital of Xiamen University · CNSun Yat-sen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood gas analyzers are capable of delivering results on electrolytes and metabolites within a few minutes and facilitate clinical decision-making. However, whether the results can be used interchangeably with values measured by chemistry analyzers remains controversial. Blood gas analyzers are capable of delivering results on electrolytes and metabolites within a few minutes and facilitate clinical decision-making. However, whether the results can be used interchangeably with values measured by chemistry analyzers remains controversial.

methodsIn total, arterial and matched venous blood samples were collected from 200 hospitalized patients. Arterial blood samples were evaluated using a RAPIDPOINT 500 to test electrolyte and glucose levels, then the samples were centrifuged and the same parameters were measured with an AU5800. Venous blood samples were processed and tested in accordance with standard operation procedures. Data were compared by using a paired t test, the agreement between the two analyzers was evaluated by using the Bland-Altman test, and sensitivity and specificity were calculated.

resultsPaired t tests showed that all parameters tested were significantly different between the two analyzers except chloride. The biases calculated indicated that blood gas analyzers tend to underestimate the parameters, and the linear regression showed a strong correlation between the two analyzers. The sensitivity, specificity and kappa values demonstrated that the diagnostic performance of blood gas analyzers is not satisfactory.

conclusionThe significant reduction in parameter estimation and diagnostic performance we observed suggested that clinicians should interpret results from blood gas analyzers more cautiously. The reference interval of blood gas analyzers should be adjusted accordingly, given that values are underestimated.

Indexed as

Automation, LaboratoryBlood Gas AnalysisBlood GlucoseElectrolytesHumansPhlebotomyPotassiumReference ValuesSensitivity and SpecificitySodiumBlood GlucoseElectrolytesPotassiumSodiumagreementblood gas analyzersdiagnostic performanceelectrolytesglucose

Identifiers

PMID32147884
PMCPMC7370720
OpenAlexW3012071106

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.