Evidence map›Paper›PMID 32147804›Full record

ArticleDrugs & aging2020

Comparison of Healthcare Resource Utilization and Costs between Rivaroxaban and Warfarin for Nonvalvular Atrial Fibrillation in a Skilled Nursing Facility Setting.

Dheeraj Mahajan, Bingcao Wu, Ji Song, Dejan Milentijevic, Veronica Ashton, V Simon Mittal

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Drugs & aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dheeraj MahajanUniversity of Illinois at Chicago and Advocate Illinois Masonic Medical Center, Melrose Park, IL, USA. dm@cimpar.com.ORCID 0000-0001-5466-9971
Bingcao WuJanssen Scientific Affairs, LLC, Titusville, NJ, USA.
Ji SongJanssen Scientific Affairs, LLC, Titusville, NJ, USA.
Dejan MilentijevicJanssen Scientific Affairs, LLC, Titusville, NJ, USA.
Veronica AshtonJanssen Scientific Affairs, LLC, Titusville, NJ, USA.
V Simon MittalCMO, Advanced Health Institute and LTC Professionals, Bloomington, MN, USA.
Janssen (United States) · USUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of direct-acting oral anticoagulants for patients with nonvalvular atrial fibrillation (NVAF) in skilled nursing facilities (SNFs) is increasing. Rivaroxaban is commonly used in this setting as an alternative to warfarin, based on comparable or increased efficacy in preventing stroke and a similar or lower risk of major bleeding.

objectiveThe aim of this study was to compare healthcare resource utilization (HCRU) and costs between NVAF patients receiving rivaroxaban or warfarin in SNFs.

methodsThis retrospective study examined de-identified claims from Optum

resultsOverall, 4423 rivaroxaban patients and 22,796 warfarin patients were identified prior to inverse probability of treatment weighting adjustment. Index SNF stay was significantly shorter among rivaroxaban-treated patients (35.8 ± 35.8 days) versus warfarin (40.1 ± 46.3 days; p < 0.0001). During the SNF stay, overall HCRU was lower for the rivaroxaban cohort versus the warfarin cohort. All-cause total costs were significantly reduced for rivaroxaban ($6450 ± $10,379) versus warfarin ($7640 ± $16,556; p < 0.0001), and similar results were observed when calculated on a PPPM basis. During the 1-year post-index period, PPPM all-cause total costs were significantly lower with rivaroxaban versus warfarin ($4135 vs. $4561; p < 0.0001).

conclusionIn this SNF setting, HCRU and costs were lower among patients with NVAF who were experienced users of rivaroxaban compared with those who were experienced users of warfarin. These findings may help inform clinical decision making to reduce the economic burden of NVAF among older adults in SNFs.

Indexed as

AgedAged, 80 and overAnticoagulantsAtrial FibrillationFemaleHealth Care CostsHumansMaleMiddle AgedPatient Acceptance of Health CareRetrospective StudiesRivaroxabanSkilled Nursing FacilitiesWarfarinAnticoagulantsRivaroxabanWarfarin

Identifiers

PMID32147804
OpenAlexW3009619710

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.