Evidence map›Paper›PMID 32147748›Full record

ReviewActa dermato-venereologica2020

Spectrum of Genetic Autoinflammatory Diseases Presenting with Cutaneous Symptoms.

Hanna Bonnekoh, Monique Butze, Tilmann Kallinich, Naotomo Kambe, Georgios Kokolakis, Karoline Krause

Open access · goldAbstract readReview
In one paragraph

Review in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. [Autoinflammatory syndromes].Zeitschrift fur Rheumatologie · 2023
    Review
  3. [Autoinflammatory syndromes].Innere Medizin (Heidelberg, Germany) · 2023
    Article
  4. Review
  5. Review
  6. Cutaneous Manifestations of Autoinflammatory Diseases.Rheumatology and immunology research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hanna Bonnekoh
Monique Butze
Tilmann Kallinich
Naotomo Kambe
Georgios Kokolakis
Karoline Krause
Charité - Universitätsmedizin Berlin · DEHumboldt-Universität zu Berlin · DEKansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoinflammatory diseases comprise a group of chronic disabling entities characterized by inflammation without the presence of infectious agents, auto-antibodies or antigen-specific T-cells. Many autoinflammatory diseases are caused by monogenic defects, which lead to disturbed immune signalling with release of proinflammatory mediators. In addition to interleukin-1β and interleukin-18, interferons play a key role in the pathophysiology of these disorders. Patients with autoinflammatory diseases show a broad variety of clinical symptoms, including skin involvement. Wheals, pustules and ulcerative lesions are the most common cutaneous findings observed. Knowledge of the clinical presentation of autoinflammatory diseases is crucial for establishing the diagnosis and guiding appropriate treatment. This review focuses on the dermatological findings in selected autoinflammatory disorders based on their distinct pathomechanisms.

Indexed as

ArthritisCryopyrin-Associated Periodic SyndromesFamilial Mediterranean FeverHereditary Autoinflammatory DiseasesHumansImmunologic Deficiency SyndromesInterferonsInterleukin-1Interleukin-18Interleukin 1 Receptor Antagonist ProteinPhospholipase C gammaSarcoidosisSkin Diseases, GeneticSynovitisUveitisInterferonsInterleukin-1Interleukin-18Interleukin 1 Receptor Antagonist ProteinPhospholipase C gammaPLCG2 protein, humanautoinflammatorygeneticsinterferoninterleukin-1

Identifiers

PMID32147748
PMCPMC9128980
OpenAlexW3011961037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.