Evidence map›Paper›PMID 32147517›Full record

ArticleJournal of molecular and cellular cardiology2020

Regulation of KCNMA1 transcription by Nrf2 in coronary arterial smooth muscle cells.

Xiaojing Sun, Ling-Ling Qian, Yong Li, Teresa M Pfiefer, Xiao-Li Wang, Hon-Chi Lee, Tong Lu

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular and cellular cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Gain-of-Function VariantCirculation. Genomic and precision medicine · 2026
    Article
  3. Impact of Sorbs2 dysfunction on cardiovascular diseases.Biochimica et biophysica acta. Molecular basis of disease · 2025
    Review
  4. Article
  5. Review
  6. Transcriptional Up-Regulation of FBXW7 by KInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Coronary Large Conductance CaFrontiers in physiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xiaojing SunThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA.
Ling-Ling QianThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA; The Department of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, 299 Qingyang Road, Wuxi 214023, Jiangsu Province, PR China.
Yong LiThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA; The Department of Cardiology, the Affiliated Wujin Hospital of Jiangsu University, Changzhou 213017, Jiangsu Province, PR China.
Teresa M PfieferThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA.
Xiao-Li WangThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA.
Hon-Chi LeeThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA.
Tong LuThe Department of Cardiovascular Medicine, Mayo Clinic, 200 First Street SW, Rochester 55905, MN, USA. Electronic address: lu.tong@mayo.edu.
Mayo Clinic · USJiangsu University · CNWuxi People's Hospital · CN

Funding

Type 2 Diabetes and Vascular BK Channel RegulationR01HL074180 · NHLBI · MAYO CLINIC ROCHESTER · PI LEE, HON-CHI · 2003 to 2018
$4.8M
Regulation of Vascular BK Channels in DiabetesR56HL074180 · NHLBI · MAYO CLINIC ROCHESTER · PI LEE, HON-CHI · 2008 to 2008
$378k
NHLBI NIH HHS R01 HL074180NHLBI NIH HHS R56 HL074180
6 · The paper itself

Abstract

The large conductance Ca

Indexed as

AnimalsCoronary VesselsHEK293 CellsHumansLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium Channel beta SubunitsMaleMiceMice, Inbred C57BLMice, KnockoutMyocytes, Smooth MuscleNF-E2-Related Factor 2Transcription, GeneticTransfectionKCNMA1 protein, humanKcnma1 protein, mouseKCNMB1 protein, humanKcnmb1 protein, mouseLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium Channel beta SubunitsNFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2Dimethyl fumarateKCNMA1KCNMB1Nrf2Transcriptional regulationVascular smooth muscle cell

Identifiers

PMID32147517
PMCPMC7140586
OpenAlexW3011826916

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.