ArticleCellular and molecular gastroenterology and hepatology2020
Targeted Intestinal Tight Junction Hyperpermeability Alters the Microbiome, Behavior, and Visceromotor Responses.
Abstract readLetter
In one paragraph
Article in Cellular and molecular gastroenterology and hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Emergence of invasiveGut microbes · 2026Article
- The gut microbiota in thrombosis.Nature reviews. Cardiology · 2025Review
- Leaky Gut Syndrome: An Interplay Between Nutrients and Dysbiosis.Current nutrition reports · 2025Review
- Tight junction regulation, intestinal permeability, and mucosal immunity in gastrointestinal health and disease.Current opinion in gastroenterology · 2025Review
- From bench to bedside: an interdisciplinary journey through the gut-lung axis with insights into lung cancer and immunotherapy.Frontiers in immunology · 2024Review
- Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice.Communications biology · 2023Article
- Transepithelial Barrier Dysfunction Drives Microbiota Dysbiosis to Initiate Epithelial Clock-driven Inflammation.Journal of Crohn's & colitis · 2023Article
- Transmission of Alzheimer's disease-associated microbiota dysbiosis and its impact on cognitive function: evidence from mice and patients.Molecular psychiatry · 2023Article
- Paracellular permeability and tight junction regulation in gut health and disease.Nature reviews. Gastroenterology & hepatology · 2023Review
- Transmission of Alzheimer's Disease-Associated Microbiota Dysbiosis and its Impact on Cognitive Function: Evidence from Mouse Models and Human Patients.Research square · 2023Article
- Shedding light on biological sex differences and microbiota-gut-brain axis: a comprehensive review of its roles in neuropsychiatric disorders.Biology of sex differences · 2022Review
- The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease.Frontiers in nutrition · 2022Review
- Tight Junctions as Targets and Effectors of Mucosal Immune Homeostasis.Cellular and molecular gastroenterology and hepatology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
O InczefiUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France; First Department of Medicine, University of Szeged, Szeged, Hungary.
V BacquiéUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
M Olier-PierreUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
M RincelUMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France.
B Ringot-DestrezUnité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d'Ascq, France.
S Ellero-SimatosUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
H EutamèneUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
C BétoulièresUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
J ThomasUMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France.
J LainéUMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France.
L GrosUMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France.
M LévêqueUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
R LeonardUnité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d'Ascq, France.
C HarkatUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
C Robbe-MasselotUnité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Villeneuve d'Ascq, France.
R RókaFirst Department of Medicine, University of Szeged, Szeged, Hungary.
M Mercier-BoninUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
V TheodorouUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France.
M DarnaudéryUMR 1286, Nutrition and Integrative Neurobiology, University of Bordeaux, French National Institute for Agriculture, Food, and Environment, Bordeaux, France.
J R TurnerLaboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: jrturner@bwh.harvard.edu.
L FerrierUMR 1331 ToxAlim, French National Institute for Agriculture, Food, and Environment, Toulouse, France. Electronic address: laurent.ferrier@inrae.fr.
Funding
ZO-1-MEDIATED PROTEIN INTERACTIONS: REGULATORS AND INTEGRATORS OF DIVERSE EPITHELIAL FUNCTIONS IN HEALTH AND DISEASER01DK061931 · NIDDK · UNIVERSITY OF CHICAGO · PI JERROLD R. TURNER · 2001 to 2026
$15.0MTherapeutic targeting of protein interactions to reverse MLCK1-mediated intestinal barrier loss and ameliorate disease.R01DK068271 · NIDDK · UNIVERSITY OF CHICAGO · PI JERROLD R. TURNER · 2005 to 2026
$11.3MNIDDK NIH HHS R01 DK061931NIDDK NIH HHS R01 DK068271
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsAnxietyBehavior, AnimalDisease Models, AnimalDysbiosisFemaleGastrointestinal MicrobiomeHumansIntestinal MucosaMaleMice, TransgenicMyosin-Light-Chain KinaseNociceptionPermeabilityTight JunctionsMyosin-Light-Chain Kinase
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.