Evidence map›Paper›PMID 32147355›Full record

ArticleBiochimica et biophysica acta. Biomembranes2020

Active S

Daniel L Drew, Brandon Butcher, Indra D Sahu, Tanbir Ahammad, Gunjan Dixit, Gary A Lorigan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochimica et biophysica acta. Biomembranes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Pinholin SBiochimica et biophysica acta. Biomembranes · 2021
    Article
  3. Article
  4. Structural and functional characterization of the pore-forming domain of pinholin SProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Structural Dynamics and Topology of the Inactive Form of SThe journal of physical chemistry. B · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniel L DrewDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: drewdl@miamioh.edu.
Brandon ButcherDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: butchebj@miamioh.edu.
Indra D SahuDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA; Natural Science Division, Campbellsville University, Campbellsville, KY 42718, USA. Electronic address: sahuid@miamioh.edu.
Tanbir AhammadDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: ahammat@miamioh.edu.
Gunjan DixitDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: dixitg@miamioh.edu.
Gary A LoriganDepartment of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: gary.lorigan@miamioh.edu.
Miami University · USCampbellsville University · US

Funding

EPR Spectroscopic Studies of Membrane Proteins-Diversity SupplementR35GM126935 · NIGMS · MIAMI UNIVERSITY OXFORD · PI GARY A LORIGAN · 2018 to 2026
$3.3M
NIGMS NIH HHS R35 GM126935
6 · The paper itself

Abstract

Pinholins are a family of lytic membrane proteins responsible for the lysis of the cytosolic membrane in host cells of double stranded DNA bacteriophages. Protein-lipid interactions have been shown to influence membrane protein topology as well as its function. This work investigated the interactions of pinholin with the phospholipid bilayer while in active and inactive confirmations to elucidate the different interactions the two forms have with the bilayer. Pinholin incorporated into deuterated DMPC-d

Indexed as

Magnetic Resonance SpectroscopyAmino Acid SequenceDeuteriumLipid BilayersMembrane ProteinsPhospholipidsDeuteriumLipid BilayersMembrane ProteinsPhospholipidsPhage lysisPhospholipid bilayersPinholinProtein-lipid interactionsSolid-state NMR

Identifiers

PMID32147355
PMCPMC7202365
OpenAlexW3009614735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.